日常步行剂量与慢性肾脏病患者的健康相关生活质量。
Daily Walking Dose and Health-related Quality of Life in Patients With Chronic Kidney Disease.
机构信息
Department of Nephrology, the Key Laboratory for the Prevention and Treatment of Chronic Kidney Disease of Chongqing, Chongqing Clinical Research Center of Kidney and Urology Diseases, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing, P.R. China.
Nursing Department, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing, P.R. China.
出版信息
J Ren Nutr. 2022 Nov;32(6):710-717. doi: 10.1053/j.jrn.2022.01.015. Epub 2022 Feb 5.
OBJECTIVE
Exercise, like daily walking, may improve overall health and impede progression of chronic kidney disease (CKD); however, no specific walking dose has been recommended for patients with CKD. We aimed to investigate the association between daily walking steps and health-related quality of life (HRQOL) in adults with CKD.
DESIGN AND METHODS
The walking steps of patients with CKD were extracted from the We Run mobile application. Their average daily walking steps were calculated and subdivided into the low-, middle-, and high-level groups. HRQOL was assessed using the physical component summary (PCS) and mental component summary (MCS) of the MOS 36 Short Form Health Survey (SF-36).
RESULTS
A total of 558 adults (50.5%, men) with an average age of 40.2 (±13.8) years were enrolled. The median daily step count was 7,404 steps. The daily walking step count demonstrated an inverse U-shaped relationship with the SF-36 and subscale scores. Participants with daily walking steps between 7,000 and 12,000 have the highest PCS (68.1 ± 12.2) and MCS scores (70.0 ± 19.5). The multiple linear regression model showed that compared with patients with a daily step count of 7,000 to 12,000, patients with a daily step count >12,000 had a significantly lower MCS score (P < .001), while patients with a daily step count <7,000 had significantly lower PCS (P < .001) and MCS scores (P = .034). Moreover, the multivariable logistic regression model showed that patients with a daily step count >12,000 had significantly lower mental health-related quality (odds ratio [OR], 2.188; 95% confidence interval [CI], 1.079-1.439 for low MCS), while those with a daily step count <7,000 had a significantly lower HRQOL than the 7,000 to 12,000 daily step count group (OR, 2.113; 95% CI, 1.203-3.711 for low PCS; OR, 2.099; 95% CI, 1.210-3.643 for low MCS).
CONCLUSIONS
These findings suggest that daily walking steps between 7,000 and 12,000 are associated with high HRQOL in adults with CKD.
目的
运动，如日常散步，可能会改善整体健康状况并延缓慢性肾脏病（CKD）的进展；然而，尚未为 CKD 患者推荐具体的散步剂量。我们旨在研究 CKD 成人每日步行步数与健康相关生活质量（HRQOL）之间的关系。
设计和方法
从 We Run 移动应用程序中提取 CKD 患者的步行步数。计算他们的平均每日步行步数，并将其细分为低、中、高水平组。使用 MOS 36 短期健康调查（SF-36）的身体成分综合评分（PCS）和心理成分综合评分（MCS）评估 HRQOL。
结果
共纳入 558 名成年人（50.5%，男性），平均年龄为 40.2（±13.8）岁。中位每日步数为 7404 步。每日步行步数与 SF-36 及其子量表评分呈反 U 型关系。每日步行步数在 7000 到 12000 步之间的参与者拥有最高的 PCS（68.1±12.2）和 MCS 评分（70.0±19.5）。多元线性回归模型显示，与每日步数为 7000 到 12000 步的患者相比，每日步数>12000 步的患者 MCS 评分明显更低（P<.001），而每日步数<7000 步的患者 PCS（P<.001）和 MCS 评分（P=.034）明显更低。此外，多变量逻辑回归模型显示，每日步数>12000 步的患者心理健康相关质量显著降低（比值比[OR]，2.188；95%置信区间[CI]，1.079-1.439 用于低 MCS），而每日步数<7000 步的患者 HRQOL 明显低于 7000 到 12000 步的每日步数组（OR，2.113；95% CI，1.203-3.711 用于低 PCS；OR，2.099；95% CI，1.210-3.643 用于低 MCS）。
结论
这些发现表明，7000 到 12000 步的每日步行步数与 CKD 成人的高 HRQOL 相关。
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