Section of Pediatric Neurosurgery, Department of Neurosurgery, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Section of Physical Medicine & Rehabilitation, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA.
World Neurosurg. 2022 May;161:5. doi: 10.1016/j.wneu.2022.01.117. Epub 2022 Feb 5.
Selective dorsal rhizotomy (SDR) has been a well-established neurosurgical treatment option for ambulatory children with spastic diplegic cerebral palsy to reduce spasticity. Outcomes for SDR for spastic lower extremity hemiparesis has been less well described. In our experience, hemi-SDR has been an excellent intervention for children with suboptimal spasticity control despite maximizing pharmacologic and chemodenervation treatments. In Video 1, we demonstrate a focal segmental hemi-SDR at the L5-S1 level in a 7-year-old male patient with spastic hemiparesis secondary to a dysembryoplastic neuroepithelial tumor in the right inferior frontoparietal area. Rhizotomy was performed with identification and selective sectioning of dorsal nerve roots with abnormal stimulation patterns as determined by electrophysiology and clinical correlation. Dorsal nerve root fibers with unsustained discharges were spared. Postoperatively, the patient participated well in inpatient and outpatient therapies with significant progress in his mobility and activities of daily living. The patient showed improvement in gait velocity (51%), internal pressure ratio (+0.05), and step length (41% on the left and 27% on the right) 20 months after hemi-SDR. He also demonstrated a step length ratio closer to 1 (0.89) showing a more equal step length bilaterally and improved weight acceptance on the affected side. There were no changes observed on the left upper extremity. This positive outcome on spasticity control and function supports the need for further prospective studies for hemi-SDR as a treatment option for children with spastic hemiparesis.
选择性脊神经后根切断术(SDR)已成为一种成熟的神经外科治疗选择,用于治疗有痉挛性双瘫脑瘫的可活动患儿,以减轻痉挛。对于痉挛性下肢偏瘫的 SDR 治疗效果描述较少。根据我们的经验,尽管对药物和化学神经切断术进行了最大程度的治疗,但对于痉挛控制不理想的儿童,半 SDR 是一种极好的干预措施。在视频 1 中,我们展示了一名 7 岁男性患儿的局限性节段性半 SDR 治疗,该患儿因右侧额顶下区发育不良性神经上皮肿瘤而导致痉挛性偏瘫。根据电生理学和临床相关性,确定了异常刺激模式后,对背根神经进行了识别和选择性切断。保留无持续放电的背根神经纤维。术后,患者很好地参与了住院和门诊治疗,在移动能力和日常生活活动方面取得了显著进展。患者的步态速度(51%)、内压比(+0.05)和步长(左侧 41%,右侧 27%)在半 SDR 后 20 个月时均有改善。他的步长比也更接近 1(0.89),表明双侧步长更均匀,受影响侧的承重能力也有所提高。左侧上肢无变化。在痉挛控制和功能方面取得的积极结果支持对半 SDR 进行进一步前瞻性研究,作为痉挛性偏瘫患儿的治疗选择。