Michaels W H, Montgomery C, Karo J, Temple J, Ager J, Olson J
Am J Obstet Gynecol. 1986 Mar;154(3):537-46. doi: 10.1016/0002-9378(86)90598-3.
To evaluate the feasibility of the use of serial ultrasound measurements of cervical length, membrane protrusion, and dilatation to discriminate between the competent and the incompetent cervix, 107 at-risk patients and 30 control subjects were examined prospectively. Patients were divided into five groups based on treatment and method of diagnosis. Epidemiologic, ultrasound, and outcome data were analyzed. Means and standard deviations for ultrasound measurements were established. Highly significant differences between all prediagnostic and postdiagnostic-pretreatment measurements were found (p less than 0.001). Highly significant differences were also found between all postdiagnostic-pretreatment and postdiagnostic-posttreatment measurements (p less than 0.001). No significant differences between prediagnostic and postdiagnostic-posttreatment measurements were noted. The incidence of preterm delivery was significantly higher among untreated diagnosed patients (p less than 0.01). By combined clinical and ultrasound criteria 51 patients (47.7%) were identified as not having cervical incompetency. Fifty-six patients (52.3%) were diagnosed.
为评估采用连续超声测量宫颈长度、胎膜突出及扩张情况以鉴别宫颈机能不全与宫颈机能正常的可行性,对107例高危患者和30例对照受试者进行了前瞻性检查。根据治疗和诊断方法将患者分为五组。分析了流行病学、超声及结局数据。确定了超声测量的均值和标准差。发现所有诊断前与诊断后-治疗前测量值之间存在高度显著差异(p<0.001)。所有诊断后-治疗前与诊断后-治疗后测量值之间也存在高度显著差异(p<0.001)。未观察到诊断前与诊断后-治疗后测量值之间存在显著差异。未经治疗的已诊断患者中早产发生率显著更高(p<0.01)。根据临床和超声联合标准,51例患者(47.7%)被确定为没有宫颈机能不全。56例患者(52.3%)被诊断为宫颈机能不全。