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早产新生儿中由解羧勒克菌引起的暴发性脓毒症:病例报告及文献复习

Fulminant Sepsis Caused by Leclercia adecarboxylata in a Premature Neonate: Case Report and Review of the Literature.

作者信息

Bronte Anaut Mónica, Arredondo Montero Javier, García Abellás Patricia, de Uribe Viloria Marta, Regojo Zapata Rita María

机构信息

From the Pathology Department.

Pediatric Surgery Department, Complejo Hospitalario de Navarra, Pamplona, Spain.

出版信息

Pediatr Infect Dis J. 2022 May 1;41(5):e220-e222. doi: 10.1097/INF.0000000000003472.

Abstract

Hospital-acquired infections are especially evident in premature infants because of prolonged stays and the need for invasive procedures. Leclercia adecarboxylata is an uncommon emerging Gram-negative bacterium that has been described in catheter and noncatheter-related infections, immunocompromised patients and less frequently affecting healthy subjects. We report a case with a postmortem diagnosis of a 24-week-old premature neonate who died as a complication of nosocomial sepsis related to an infection by L. adecarboxylata. Although the cases of L. adecarboxylata infection in children have been rarely reported, this case appears to be the first in which an infection by L. adecarboxylata is accompanied by focal spontaneous ileal perforation.

摘要

由于住院时间延长和需要进行侵入性操作,医院获得性感染在早产儿中尤为明显。去羧勒克菌是一种罕见的新兴革兰氏阴性菌,已在导管相关和非导管相关感染、免疫功能低下患者中被描述,较少感染健康受试者。我们报告一例24周龄早产新生儿的尸检诊断病例,该患儿因去羧勒克菌感染导致医院感染性败血症并发症死亡。虽然儿童去羧勒克菌感染的病例很少报道,但该病例似乎是首例去羧勒克菌感染伴有局灶性自发性回肠穿孔的病例。

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