Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan.
Aesthet Surg J. 2022 Aug 24;42(9):NP579-NP588. doi: 10.1093/asj/sjac024.
The main drawback of fat transfer breast augmentation is the need for multiple sessions of fat injection. For approximately 15 years, stem cells and the Brava device for breast expansion have been discussed and extensively investigated to address relevant challenges. However, the safety and effectiveness of autologous fat transfer as a single-session primary breast augmentation technique has not yet been standardized.
The aim of this study was to achieve mega volume fat breast augmentation in a single session by developing a "space-creating" approach that emphasizes the use of highly purified fat to achieve an optimized surgical outcome with large-volume breast augmentation.
Female patients who underwent aesthetic breast augmentation (October 2013-October 2020) involving the application of this space-creating technique for mega volume autologous fat transfer were retrospectively enrolled. Inclusion criteria were patients with hypomastia, breast asymmetry, and volume replacement following implant removal with BMI ≥18.5 kg/m2. After macrospace creation, highly purified fat was injected in several rounds during the procedure. A breast massage was performed between each stage (microspace creation). Breast circumference, nipple-inframammary fold distance, and cup size were recorded during 6 months of follow-up.
Three hundred fifty-eight patients met the inclusion criteria. Average fat injection volumes of 510.9 mL in the right breast and 490.8 mL in the left breast resulted in at least a 2 cup size increase. The significant outcome remained stable at 6 months after surgery.
The space-creating technique and the injection of highly purified fat achieves stable cosmetic outcomes of mega volume breast augmentation in a single session.
脂肪转移乳房增大的主要缺点是需要多次脂肪注射。大约 15 年来，干细胞和用于乳房扩张的 Brava 设备一直被讨论和广泛研究，以解决相关挑战。然而，自体脂肪转移作为单次原发性乳房增大技术的安全性和有效性尚未标准化。
本研究的目的是通过开发一种“创造空间”的方法来实现单次大体积脂肪乳房增大，该方法强调使用高度纯化的脂肪，以实现大体积乳房增大的优化手术效果。
回顾性纳入 2013 年 10 月至 2020 年 10 月间接受美学乳房增大（涉及应用这种创造空间技术进行大体积自体脂肪转移）的女性患者。纳入标准为乳房下垂、乳房不对称和 BMI≥18.5kg/m2 植入物取出后需要体积置换的患者。在创建宏观空间后，在手术过程中分几轮注射高度纯化的脂肪。在每个阶段（微空间创建）之间进行乳房按摩。在 6 个月的随访期间记录乳房周长、乳头下皱襞距离和罩杯尺寸。
符合纳入标准的 358 例患者。右乳房平均注射 510.9ml 脂肪，左乳房平均注射 490.8ml 脂肪，结果至少增加了 2 个罩杯。手术后 6 个月，显著结果保持稳定。
创造空间技术和注射高度纯化的脂肪可在单次手术中实现大体积乳房增大的稳定美容效果。
