Husby G, Arora R, Williams R C, Khaw B A, Haber E, Butler C
Arthritis Rheum. 1986 Feb;29(2):207-11. doi: 10.1002/art.1780290208.
We studied cardiac tissues of a patient who died of severe rheumatic myocarditis. Multiple Aschoff lesions were present throughout both ventricles and auricles. Immunofluorescence studies showed large monocytoid cells staining with OKM1 and anti-Leu M-3 as well as anti-Ia. Scattered T cells in areas of focal myocarditis stained with OKT3. Parallel staining for cardiac myosin-heavy chain antigens showed patchy dissolution of cardiac muscle fibers and traces of cardiac myosin within large monocytoid Aschoff cells.
我们研究了一名死于严重风湿性心肌炎患者的心脏组织。两个心室和心房均存在多个阿绍夫小体。免疫荧光研究显示，大单核样细胞用OKM1、抗Leu M-3以及抗Ia染色。局灶性心肌炎区域的散在T细胞用OKT3染色。心肌肌球蛋白重链抗原的平行染色显示心肌纤维呈片状溶解，且在大单核样阿绍夫细胞内有微量心肌肌球蛋白。
