Ignacio Chavez National Institute for Cardiology - Echocardiography, Juan Badiano - México.
Medical Society of 20 of November National Medical Center - Cardiology, Mexico City - México.
Arq Bras Cardiol. 2022 May;118(5):885-893. doi: 10.36660/abc.20201384.
Schistosomiasis is a Neglected Tropical Disease which may lead to cardiovascular (CV) complications. However, the CV involvement in schistosomiasis has yet to be fully elucidated due to the limited number of cases and lack of reliable evidence, as schistosomiasis typically occurs in locations without adequate infrastructure for robust data collection.
This systematic review aims to assess cardiovascular implications of schistosomiasis, including in the diagnosis and treatment, and propose an algorithm for screening of CV manifestations.
A systematic review was performed in the MEDLINE/PubMed and LILACS databases of articles on the CV involvement in schistosomiasis.
Thirty-three records were considered for this review: six review articles, one systematic review, one clinical trial, 14 observational studies, seven case reports, and four cases series. CV involvement includes a wide spectrum of clinical conditions, such as myocardial ischemia, ventricular dysfunction, myocarditis, pulmonary arterial hypertension, and pericarditis.
Cardiac complications of schistosomiasis may cause long-term disability and death. Clinical monitoring, physical examination, early electrocardiogram, and echocardiogram should be considered as key measures to detect CV involvement. Due to the lack of effective treatment of complications, sanitation and education in endemic areas are necessary for the elimination of this global health problem.
血吸虫病是一种被忽视的热带病，可能导致心血管（CV）并发症。然而，由于病例数量有限且缺乏可靠证据，血吸虫病的 CV 受累情况仍未得到充分阐明，因为血吸虫病通常发生在基础设施不完善、无法进行稳健数据收集的地方。
本系统评价旨在评估血吸虫病的心血管影响，包括在诊断和治疗中的影响，并提出一种用于筛查 CV 表现的算法。
在 MEDLINE/PubMed 和 LILACS 数据库中对有关血吸虫病 CV 受累的文章进行了系统评价。
共考虑了 33 份记录进行综述：6 篇综述文章、1 篇系统评价、1 项临床试验、14 项观察性研究、7 份病例报告和 4 份病例系列。CV 受累包括广泛的临床情况，如心肌缺血、心室功能障碍、心肌炎、肺动脉高压和心包炎。
血吸虫病的心脏并发症可能导致长期残疾和死亡。临床监测、体格检查、早期心电图和超声心动图应被视为检测 CV 受累的关键措施。由于缺乏对并发症的有效治疗，在流行地区进行卫生和教育对于消除这一全球健康问题是必要的。
