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Utilizing Longitudinal Within-Individual Changes of Serum Creatinine, Cystatin C, and/or eGFR to Optimize Clinical Sensitivity and Eliminate Race and Gender Corrections.

作者信息

Toffaletti John G, Burke Cyril O, Bayliss George, Lynch Matthew

机构信息

Duke University Medical Center, Department of Pathology/Clinical Laboratories, Durham, NC, USA.

Alpert-Brown Medical School, Medical Staff at The Miriam Hospital, Providence, RI, USA.

出版信息

J Appl Lab Med. 2022 May 4;7(3):807-811. doi: 10.1093/jalm/jfac001.

DOI:10.1093/jalm/jfac001
PMID:35138380
Abstract
摘要

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Differential estimation of CKD using creatinine- versus cystatin C-based estimating equations by category of body mass index.根据体重指数类别，使用基于肌酐和胱抑素C的估算方程对慢性肾脏病进行差异估计。
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Cystatin C-based glomerular filtration rate associates more closely with mortality than creatinine-based or combined glomerular filtration rate equations in unselected patients.在未经过挑选的患者中，基于胱抑素C的肾小球滤过率与死亡率的关联比基于肌酐或联合的肾小球滤过率方程更为密切。
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Age- and sex-specific reference limits for creatinine, cystatin C and the estimated glomerular filtration rate.年龄和性别特异性肌酐、胱抑素 C 和肾小球滤过率估算值的参考范围。
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The Estimation of Glomerular Filtration Rate Based on the Serum Cystatin C and Creatinine Values.基于血清胱抑素C和肌酐值估算肾小球滤过率
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[Use of cystatin C to estimate glomerular filtration rate].[使用胱抑素C估算肾小球滤过率]
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Cystatin C as a biomarker for estimating glomerular filtration rate.胱抑素C作为评估肾小球滤过率的生物标志物。
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