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耳硬化症患者计算机断层扫描密度测定的稳定性:两年随访

Stability of computed tomography densitometry in patients with otosclerosis:a two-year follow-up.

作者信息

Fang Yanqing, Chen Wei, Ren Liu-Jie, Kiehn Sebastian, Shu Yilai, Chen Bing

机构信息

ENT Institute and Otorhinolaryngology Department of the Affiliated Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200031, China.

NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, PR China.

出版信息

J Otol. 2022 Jan;17(1):39-45. doi: 10.1016/j.joto.2021.10.003. Epub 2021 Nov 8.

Abstract

OBJECTIVES

To quantify the progression of otosclerosis in the unoperated ear between two stapedotomy procedures for patients with bilateral otosclerosis which can help to determine whether a HRCT scan should be re-performed before the second surgery for patients who already received HRCT imaging before the initial surgery.

METHODS

35 patients who underwent bilateral stapedotomy were included. Two rounds of HRCT examination and audiometry were performed at the time of the first surgery and second surgery on the ear that was not operated on during the initial surgery. The relationship between the changes in HRCT densitometry and audiometry over time was analyzed.

RESULTS

The second round of HRCT did not add significant information about the changes to the otosclerosis lesions in either the imaging diagnosis or the HRCT density values except for small changes in the HRCT densitometry readings at the area anterior to the inner auditory (P = 0.01). While the changes in HRCT manifestation are small, changes near the fissula ante fenestram (FAF) were still positively correlated with the air bone gap (ABG) of patients (p = 0.031, r = 0.388).

CONCLUSIONS

The progression of lesions in otosclerosis is slow resulting in small and insignificant changes to the HRCT features. Therefore, a repeat HRCT evaluations prior to surgery is not necessary for patients who have had a previous HRCT evaluation within 2 years of the operation. The small changes in HRCT manifestation near the FAF were still correlated with negative effects on the ABG which could cause worsened hearing thresholds over this timeframe.

摘要

目的

量化双侧耳硬化症患者在两次镫骨手术之间未手术耳的耳硬化进展情况,这有助于确定对于初次手术前已接受高分辨率计算机断层扫描(HRCT)成像的患者,在第二次手术前是否应再次进行HRCT扫描。

方法

纳入35例行双侧镫骨手术的患者。在初次手术和第二次手术时,对初次手术未操作的耳进行两轮HRCT检查和听力测定。分析HRCT密度测定值和听力测定随时间的变化关系。

结果

第二轮HRCT除了在内听道前方区域的HRCT密度测定读数有微小变化外(P = 0.01),在成像诊断或HRCT密度值方面,均未增加有关耳硬化病变变化的重要信息。虽然HRCT表现变化较小,但窗前裂(FAF)附近的变化仍与患者的气骨导间距(ABG)呈正相关(p = 0.031,r = 0.388)。

结论

耳硬化症病变进展缓慢,导致HRCT特征变化微小且不显著。因此,对于在手术2年内已进行过HRCT评估的患者,术前无需重复进行HRCT评估。FAF附近HRCT表现的微小变化仍与对ABG的负面影响相关,这可能在此时间段内导致听力阈值恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e79b/8811413/65d4dc30f733/gr1.jpg

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