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界定近期出狱的艾滋病毒感染高危男性的暴露前预防护理连续过程:一项前瞻性队列研究方案

Defining the Pre-exposure Prophylaxis Care Continuum Among Recently Incarcerated Men at High Risk for HIV Infection: Protocol for a Prospective Cohort Study.

作者信息

Murphy Matthew, Sosnowy Collette, Rogers Brooke, Napoleon Siena, Galipeau Drew, Scott Ty, Tao Jun, Berk Justin, Clarke Jennifer, Nunn Amy, Chan Philip A

机构信息

Brown University, Providence, RI, United States.

The Miriam Hospital, Providence, RI, United States.

出版信息

JMIR Res Protoc. 2022 Feb 10;11(2):e31928. doi: 10.2196/31928.

Abstract

BACKGROUND

HIV disproportionately impacts criminal justice-involved individuals, including men who experience incarceration. Men make up the vast majority of those experiencing incarceration as well as those newly diagnosed with HIV infection. Pre-exposure prophylaxis (PrEP) is a highly effective biomedical intervention that significantly reduces the risk of HIV acquisition. However, implementation in criminal justice systems is limited. Little is known about effective PrEP implementation and use in this unique public health context.

OBJECTIVE

The aim of this study is to characterize the experience of implementing PrEP clinical care in a criminal justice setting for men vulnerable to HIV acquisition.

METHODS

This article describes a PrEP care continuum for men experiencing incarceration who are at increased risk of HIV acquisition, which can help conceptualize approaches to evaluating PrEP implementation.

RESULTS

The outlined study will enroll 100 men experiencing incarceration at high risk for HIV acquisition prior to release into the community. The goal is to initiate PrEP prior to release and link individuals to PrEP providers in the community, capturing barriers and facilitators to PrEP use during this uniquely vulnerable time period for HIV acquisition.

CONCLUSIONS

Based on the proposed care continuum and what is known about HIV risk and prevention efforts in the criminal justice context, we outline key future research efforts to better understand effective approaches to preventing HIV infection among this vulnerable population. The described approach presents a powerful public health opportunity to help end the HIV epidemic.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/31928.

摘要

背景

艾滋病毒对涉及刑事司法的人群影响尤为严重,包括经历监禁的男性。男性占经历监禁以及新诊断出感染艾滋病毒人群的绝大多数。暴露前预防(PrEP)是一种高效的生物医学干预措施,可显著降低感染艾滋病毒的风险。然而,在刑事司法系统中的实施情况有限。对于在这种独特的公共卫生背景下有效实施和使用PrEP的情况,人们了解甚少。

目的

本研究的目的是描述在刑事司法环境中为易感染艾滋病毒的男性实施PrEP临床护理的经验。

方法

本文描述了一个针对经历监禁且感染艾滋病毒风险增加的男性的PrEP护理连续过程,这有助于构思评估PrEP实施情况的方法。

结果

概述的研究将招募100名在释放到社区之前感染艾滋病毒风险高的经历监禁的男性。目标是在释放前启动PrEP,并将个人与社区中的PrEP提供者联系起来,捕捉在这个艾滋病毒感染特别脆弱的时期使用PrEP的障碍和促进因素。

结论

基于拟议的护理连续过程以及在刑事司法背景下已知的艾滋病毒风险和预防措施,我们概述了未来的关键研究工作,以更好地了解在这一脆弱人群中预防艾滋病毒感染的有效方法。所描述的方法提供了一个强大的公共卫生机会,以帮助终结艾滋病毒流行。

国际注册报告识别码(IRRID):DERR1-10.2196/31928。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aab8/8874820/937eb3b7b573/resprot_v11i2e31928_fig1.jpg

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