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It takes two to bleed: anticoagulation intensity and the host's vascular susceptibility.

作者信息

Seeliger Benjamin, Wendel-Garcia Pedro David, Stahl Klaus, Bode Christian, David Sascha

机构信息

Hannover Medical School, Department of Respiratory Medicine and Biomedical Research in End-Stage and Obstructive Lung Disease Hannover, German Center for Lung Research, Hannover, Germany.

Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland.

出版信息

Intensive Care Med. 2022 May;48(5):619-620. doi: 10.1007/s00134-022-06643-y. Epub 2022 Feb 10.

DOI:10.1007/s00134-022-06643-y
PMID:35142897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8830966/
Abstract
摘要

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It takes two to bleed: anticoagulation intensity and the host's vascular susceptibility. Author's reply.出血涉及两个因素：抗凝强度和宿主血管易感性。作者回复。
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Reduced anticoagulation strategy is associated with a lower incidence of intracerebral hemorrhage in COVID-19 patients on extracorporeal membrane oxygenation.在接受体外膜肺氧合治疗的新冠肺炎患者中，降低抗凝策略与脑出血发生率较低相关。
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It takes two to bleed: anticoagulation intensity and the host's vascular susceptibility. Author's reply.出血涉及两个因素：抗凝强度和宿主血管易感性。作者回复。
Intensive Care Med. 2022 May;48(5):621-623. doi: 10.1007/s00134-022-06636-x. Epub 2022 Mar 14.

本文引用的文献

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Intracranial Hemorrhages on Extracorporeal Membrane Oxygenation: Differences Between COVID-19 and Other Viral Acute Respiratory Distress Syndrome.体外膜肺氧合患者的颅内出血：COVID-19 与其他病毒性急性呼吸窘迫综合征的差异。
Crit Care Med. 2022 Jun 1;50(6):e526-e538. doi: 10.1097/CCM.0000000000005441. Epub 2022 Jan 12.
2
Bleeding and thrombotic events in adults supported with venovenous extracorporeal membrane oxygenation: an ELSO registry analysis.体外膜肺氧合支持成人的出血和血栓事件：ELSO 登记分析。
Intensive Care Med. 2022 Feb;48(2):213-224. doi: 10.1007/s00134-021-06593-x. Epub 2021 Dec 18.
3
A Comparison of Thrombosis and Hemorrhage Rates in Patients With Severe Respiratory Failure Due to Coronavirus Disease 2019 and Influenza Requiring Extracorporeal Membrane Oxygenation.新冠肺炎和需要体外膜肺氧合的流感导致严重呼吸衰竭患者的血栓形成和出血率比较。
Crit Care Med. 2021 Jul 1;49(7):e663-e672. doi: 10.1097/CCM.0000000000004971.
4
Comparison of anticoagulation strategies for veno-venous ECMO support in acute respiratory failure.比较急性呼吸衰竭患者静脉-静脉体外膜肺氧合支持的抗凝策略。
Crit Care. 2021 Jan 4;24(1):701. doi: 10.1186/s13054-020-03348-w.
5
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.新型冠状病毒肺炎的肺血管内皮细胞炎症、血栓形成和血管生成。
N Engl J Med. 2020 Jul 9;383(2):120-128. doi: 10.1056/NEJMoa2015432. Epub 2020 May 21.