Hippen Benjamin E, Axelrod David A, Maher Kennan, Li Ruixin, Kumar Deepali, Caliskan Yasar, Alhamad Tarek, Schnitzler Mark, Lentine Krista L
Fresenius Medical Care, Charlotte, North Carolina.
University of Iowa Transplant Institute, Iowa City, Iowa.
Am J Transplant. 2022 Jun;22(6):1705-1713. doi: 10.1111/ajt.16995. Epub 2022 Mar 1.
An electronic survey canvassing current policies of transplant centers regarding a COVID-19 vaccine mandate for transplant candidates and living donors was distributed to clinicians at US solid organ transplant centers performing transplants from October 14, 2021-November 15, 2021. Responses were received from staff at 141 unique transplant centers. These respondents represented 56.4% of US transplant centers, and responding centers performed 78.5% of kidney transplants and 82.4% of liver transplants in the year prior to survey administration. Only 35.7% of centers reported implementing a vaccine mandate, while 60.7% reported that vaccination was not required. A minority (42%) of responding centers with a vaccine mandate for transplant candidates also mandated vaccination for living organ donors. Centers with a vaccine mandate most frequently cited clinical evidence supporting the efficacy of pre-transplant vaccination (82%) and stewardship obligations to ensure organs were transplanted into the lowest risk patients (64%). Centers without a vaccine mandate cited a variety of reasons including administrative, equity, and legal considerations for their decision. Transplant centers in the United States exhibit significant heterogeneity in COVID-19 vaccination mandate policies for transplant candidates. While all centers encourage vaccination, most centers have not mandated COVID-19 vaccination for candidates and living donors, citing administrative opposition, legal prohibitions, and concern about equity in access to transplants.
一项关于移植中心针对移植候选者和活体供者实施新冠疫苗强制接种现行政策的电子调查,于2021年10月14日至2021年11月15日分发给美国实体器官移植中心进行移植手术的临床医生。收到了来自141个不同移植中心工作人员的回复。这些受访者代表了美国移植中心的56.4%,且在调查实施前一年,回复中心进行了78.5%的肾移植和82.4%的肝移植。只有35.7%的中心报告实施了疫苗强制接种,而60.7%的中心报告不需要接种疫苗。少数(42%)对移植候选者实施疫苗强制接种的回复中心也对活体器官供者强制接种疫苗。实施疫苗强制接种的中心最常引用支持移植前接种疫苗有效性的临床证据(82%)以及确保器官移植到风险最低患者身上的管理义务(64%)。未实施疫苗强制接种的中心列举了各种原因,包括行政、公平性和法律方面的考虑因素。美国的移植中心在针对移植候选者的新冠疫苗强制接种政策方面存在显著差异。虽然所有中心都鼓励接种疫苗,但大多数中心并未对候选者和活体供者强制实施新冠疫苗接种,理由包括行政方面的反对、法律禁令以及对移植获取公平性的担忧。