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在美国,在进行肾移植手术前强制接种 COVID-19 疫苗:没有解决方案,只有决策。

Mandating COVID-19 vaccination prior to kidney transplantation in the United States: No solutions, only decisions.

机构信息

Department of Transplant Medicine, Fresenius Medical Care, Charlotte, North Carolina.

出版信息

Am J Transplant. 2022 Feb;22(2):381-385. doi: 10.1111/ajt.16891. Epub 2021 Nov 24.

DOI:10.1111/ajt.16891
PMID:34780109
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8652664/
Abstract

The question of whether transplant clinicians should mandate COVID-19 vaccination as a condition of transplant candidacy is complex. A vaccine mandate may be defensible on the grounds that transplant clinicians are obligated to ensure transplantation is conducted safely, and in a manner that entails the best use of a scarce public good. However, mandate proponents will inexorably predicate their arguments on contingent clinical judgments that meliorate rather than resolve core value disagreements. Vaccine mandates are conceivably defensible on narrow grounds, but may prove to be purchased at the expense of an attenuation of shared decision-making, proffering claims of risk reduction from a vaccine mandate beyond what the current evidence base supports, and unintentionally exacerbating durable inequities in access to transplantation.

摘要

移植临床医生是否应该将 COVID-19 疫苗接种作为移植候选条件的问题很复杂。从移植临床医生有义务确保移植安全进行,并且以最佳利用稀缺公共资源的方式进行的角度来看,疫苗强制接种可能是有道理的。然而,强制接种的支持者将不可避免地根据改善而不是解决核心价值观分歧的偶然临床判断来预先判断他们的论点。疫苗强制接种在狭隘的范围内可能是有道理的,但可能会以削弱共享决策为代价,提出疫苗强制接种可以降低风险的主张,超出当前证据基础所支持的范围,并无意中加剧获得移植的持久不平等。

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Mandating COVID-19 vaccination prior to kidney transplantation in the United States: No solutions, only decisions.在美国,在进行肾移植手术前强制接种 COVID-19 疫苗:没有解决方案,只有决策。
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Pediatr Transplant. 2023 Feb;27(1):e14408. doi: 10.1111/petr.14408. Epub 2022 Oct 9.
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本文引用的文献

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Risks and Benefits of Kidney Transplantation during the COVID-19 Pandemic: Transplant or Not Transplant?COVID-19 大流行期间肾移植的风险和获益:移植还是不移植?
Kidney360. 2021 May 13;2(7):1179-1187. doi: 10.34067/KID.0002532021. eCollection 2021 Jul 29.
2
Impact of rituximab on humoral response to COVID-19 booster vaccine and antibody kinetics in patients with anti-neutrophil cytoplasmic antibody vasculitis.利妥昔单抗对抗中性粒细胞胞浆抗体血管炎患者针对新冠病毒加强疫苗的体液反应及抗体动力学的影响
Kidney Int. 2021 Nov;100(5):1124-1127. doi: 10.1016/j.kint.2021.08.020. Epub 2021 Sep 7.
3
Antibody and T Cell Response to SARS-CoV-2 Messenger RNA BNT162b2 Vaccine in Kidney Transplant Recipients and Hemodialysis Patients.肾移植受者和血液透析患者对 SARS-CoV-2 信使 RNA BNT162b2 疫苗的抗体和 T 细胞反应。
J Am Soc Nephrol. 2021 Sep;32(9):2147-2152. doi: 10.1681/ASN.2021040480. Epub 2021 Jun 10.
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High immunogenicity of a messenger RNA-based vaccine against SARS-CoV-2 in chronic dialysis patients.mRNA 疫苗对慢性透析患者 SARS-CoV-2 具有高免疫原性。
Nephrol Dial Transplant. 2021 Aug 27;36(9):1704-1709. doi: 10.1093/ndt/gfab193.
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Absence of Humoral Response After Two-Dose SARS-CoV-2 Messenger RNA Vaccination in Patients With Rheumatic and Musculoskeletal Diseases: A Case Series.风湿性和肌肉骨骼疾病患者接种两剂严重急性呼吸综合征冠状病毒2信使核糖核酸疫苗后无体液免疫反应:病例系列
Ann Intern Med. 2021 Sep;174(9):1332-1334. doi: 10.7326/M21-1451. Epub 2021 May 25.
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Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients.实体器官移植受者对两剂严重急性呼吸综合征冠状病毒2信使核糖核酸疫苗系列的抗体反应。
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Immune response to SARS-CoV-2 infection and vaccination in patients receiving kidney replacement therapy.肾替代治疗患者中对 SARS-CoV-2 感染和疫苗接种的免疫反应。
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Racism, disease, and vaccine refusal: People of color are dying for access to COVID-19 vaccines.种族主义、疾病和疫苗拒绝:有色人种为获得 COVID-19 疫苗而死亡。
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