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糖尿病女性的避孕措施使用情况及与妊娠相关的知识

Contraception use and knowledge related to pregnancy in diabetic women.

作者信息

Feutry Louise, Barbe Coralie, Marquet-Dupont Aurélie, Fèvre Anne, Lukas-Croisier Céline, Vitellius Géraldine, Delemer Brigitte, Barraud Sara

机构信息

CHU de Reims, Hôpital Robert-Debré, Service d'Endocrinologie - Diabète - Nutrition, avenue du Général-Koenig, 51092 Reims cedex, France.

Comité Universitaire de Ressources pour la Recherche en Santé, Université de Reims Champagne-Ardenne UFR Médecine, 51, rue Cognacq-Jay, 51100 Reims, France.

出版信息

Ann Endocrinol (Paris). 2022 Apr;83(2):88-94. doi: 10.1016/j.ando.2022.01.007. Epub 2022 Feb 7.

Abstract

BACKGROUND

Diabetes mellitus prevalence is increasing among women of child-bearing age. Diabetic pregnancy is associated with major maternal and fetal risks, and these can be reduced by preconception care. Pregnancy can be planned using appropriate effective contraception. The objective of this study was to assess diabetic patients' knowledge about pregnancy and to describe their contraceptive use.

STUDY DESIGN

An observational study was conducted from February to July 2020 at Reims University Hospital, France. Inclusion criteria were: women aged 18 to 40years, with type 1 (T1D) or type 2 diabetes (T2D). Patients filled out a survey about contraceptive use and knowledge regarding diabetic pregnancy and data were completed from medical records.

RESULTS

Eighty-nine T1D and 33 T2D patients were included, with mean ages of 27.9±6.3 and 32.6±4.6years, respectively. Seventy-five percent reported that they had been informed about pregnancy-related risks and 67% about the need to plan pregnancy. The preconception HbA1c target was known by 33% of patients. Appropriate knowledge about pregnancy was greater in T1D patients (65.9%, versus 36.4% in T2D patients; P=0.003). The rate of patients using an effective contraceptive method was 66.4%. Fifteen percent patients for whom contraception was recommended reported having no contraceptive method; 12.5% of contraception users were using a contraindicated method.

CONCLUSION

A large majority of diabetic women were aware of pregnancy-related risks and the importance of pregnancy planning, but there are still gaps, especially in T2D patients. We need to improve our practices by providing more information and better access to appropriate effective contraception.

GOV NUMBER

NCT04350879.

摘要

背景

育龄女性中糖尿病的患病率正在上升。糖尿病妊娠与孕产妇和胎儿的重大风险相关,而孕前护理可降低这些风险。可使用适当有效的避孕措施来计划妊娠。本研究的目的是评估糖尿病患者对妊娠的了解情况,并描述他们的避孕措施使用情况。

研究设计

2020年2月至7月在法国兰斯大学医院进行了一项观察性研究。纳入标准为:年龄在18至40岁之间,患有1型糖尿病(T1D)或2型糖尿病(T2D)的女性。患者填写了一份关于避孕措施使用情况以及糖尿病妊娠相关知识的调查问卷,并从病历中获取补充数据。

结果

纳入了89例T1D患者和33例T2D患者,平均年龄分别为27.9±6.3岁和32.6±4.6岁。75%的患者报告称他们已被告知与妊娠相关的风险,67%的患者了解计划妊娠的必要性。33%的患者知道孕前糖化血红蛋白(HbA1c)目标。T1D患者对妊娠的适当了解程度更高(65.9%,而T2D患者为36.4%;P = 0.003)。使用有效避孕方法的患者比例为66.4%。在被建议采取避孕措施的患者中,15%报告没有采取任何避孕措施;12.5%的避孕措施使用者采用了禁忌方法。

结论

绝大多数糖尿病女性了解与妊娠相关的风险以及妊娠计划的重要性,但仍存在差距,尤其是在T2D患者中。我们需要通过提供更多信息并更好地提供适当有效的避孕措施来改进我们的做法。

政府编号

NCT04350879。

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