Wu Zehui, Liu Defeng, Peng Shihao, Wang Yuejun, Zhan Xiaolin, Li Laibin, Wan Hong, Li Yangyang, Guo Tao, Xu Aman
Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Department of General Surgery, The Fourth Affiliated Hospital of Anhui Medical University, Hefei, China.
Front Surg. 2022 Jan 25;8:800563. doi: 10.3389/fsurg.2021.800563. eCollection 2021.
Pleomorphic adenomas (PAs) are the most common benign salivary neoplasms. PAs are generally slow-growing but may sometimes become aggressive and grow rapidly within a short period of time. Here, we report the case of an 83-year-old Chinese woman with an anterior neck mass that had been growing over the past 30 years. She felt uncomfortable because the mass had grown quite rapidly in the past year. The final diagnosis of a PA of the left submandibular gland was confirmed by histopathological and immunohistochemical examinations after surgical resection. Our patient recalled a history of an excision of a neck mass 40 years prior to presentation at another hospital. Based on our imaging findings and surgical findings, we speculate that the neck mass 40 years prior may also have been a PA. Our case reminds us the rare recurrence possibility of PAs, and early and thorough resection may have a good prognosis. In addition, to the best of our knowledge, this is the largest PA of the submandibular gland reported to date.
多形性腺瘤（PAs）是最常见的涎腺良性肿瘤。多形性腺瘤通常生长缓慢，但有时可能会变得具有侵袭性，并在短时间内迅速生长。在此，我们报告一例83岁中国女性病例，其颈部前方肿物已生长30年。由于肿物在过去一年中生长相当迅速，她感到不适。手术切除后，经组织病理学和免疫组化检查确诊为左下颌下腺多形性腺瘤。我们的患者回忆起在此次就诊40年前曾在另一家医院切除过颈部肿物。根据我们的影像学和手术结果，我们推测40年前的颈部肿物可能也是多形性腺瘤。我们的病例提醒我们多形性腺瘤存在罕见的复发可能性，早期彻底切除可能预后良好。此外，据我们所知，这是迄今为止报道的最大的下颌下腺多形性腺瘤。
