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内镜下黏膜下剥离术治疗侧向扩散型壶腹癌。

Endoscopic submucosal dissection for a laterally spreading ampullary carcinoma.

作者信息

Dohi Osamu, Ishida Tsugitaka, Doi Toshifumi, Yoshida Naohisa, Itoh Yoshito

机构信息

Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, Japan.

出版信息

VideoGIE. 2021 Dec 17;7(2):79-81. doi: 10.1016/j.vgie.2021.11.001. eCollection 2022 Feb.

DOI:10.1016/j.vgie.2021.11.001
PMID:35146232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8819520/
Abstract

Video 1We performed endoscopic submucosal dissection with the patient under conscious sedation. After making markings around the lesion, we incised the mucosa from the oral side of the ampullary lesion and dissected the submucosal layer using a Clutch Cutter. We created 2 submucosal tunnels to identify the dissection line of the ampulla. After completion of the tunnels, we performed a mucosal incision circumferentially and dissected the submucosal layer except the ampulla. Subsequently, we removed the ampulla directly above the muscle layer of the duodenum using the Clutch Cutter. En bloc resection was achieved. After resecting the lesion, a biliary stent and pancreatic stent were placed into the common bile duct and pancreatic duct, respectively. Prophylactic closure of the mucosal defect was performed using endoclips and a polyglycolic acid sheet with fibrin glue to prevent delayed perforation and bleeding.

摘要

视频1

我们在患者清醒镇静状态下进行了内镜黏膜下剥离术。在病变周围做好标记后,我们从壶腹病变的口腔侧切开黏膜,并使用圈套切割器剥离黏膜下层。我们创建了两条黏膜下隧道以确定壶腹的剥离线。完成隧道后,我们进行了环形黏膜切开,并剥离了除壶腹外的黏膜下层。随后,我们使用圈套切割器在十二指肠肌层正上方切除壶腹。实现了整块切除。切除病变后,分别在胆总管和胰管内放置了胆管支架和胰管支架。使用内镜夹和带有纤维蛋白胶的聚乙醇酸片对黏膜缺损进行预防性封闭,以防止延迟穿孔和出血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/666a/8819520/c042ebfacf37/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/666a/8819520/0a3901d2e86c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/666a/8819520/c042ebfacf37/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/666a/8819520/0a3901d2e86c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/666a/8819520/c042ebfacf37/gr2.jpg

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Endoscopy. 2023 Dec;55(S 01):E92-E93. doi: 10.1055/a-1934-9641. Epub 2022 Oct 10.

本文引用的文献

1
Endoscopic papillectomy for neoplastic ampullary lesions: A systematic review with pooled analysis.肿瘤性壶腹病变的内镜乳头切除术:一项汇总分析的系统评价
United European Gastroenterol J. 2020 Feb;8(1):44-51. doi: 10.1177/2050640619868367. Epub 2019 Jul 30.
2
Efficacy and safety of endoscopic submucosal dissection using a scissors-type knife with prophylactic over-the-scope clip closure for superficial non-ampullary duodenal epithelial tumors.内镜黏膜下剥离术联合预防性内镜下黏膜切除术用钛夹治疗非壶腹型十二指肠浅表层上皮性肿瘤的疗效及安全性
Dig Endosc. 2020 Sep;32(6):904-913. doi: 10.1111/den.13618. Epub 2020 Feb 5.
3
Endoscopic resection of advanced and laterally spreading duodenal papillary tumors.
晚期及侧向扩散十二指肠乳头肿瘤的内镜切除术
Dig Endosc. 2016 Mar;28(2):121-30. doi: 10.1111/den.12574. Epub 2015 Dec 17.
4
Focal early stage cancer in ampullary adenoma: surgery or endoscopic papillectomy?壶腹腺瘤中的局灶早期癌:手术还是内镜下乳头切除术?
Gastrointest Endosc. 2007 Oct;66(4):701-7. doi: 10.1016/j.gie.2007.02.049.