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COVID-19 大流行期间儿科肝移植受者的治疗依从性和行为。

Treatment adherence and behavior of pediatric liver transplant recipients during the COVID-19 pandemic.

机构信息

Schneider Children's Medical Center, Institute of Gastroenterology, Nutrition and Liver Diseases, Petach Tikva, Israel.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Pediatr Transplant. 2022 Jun;26(4):e14250. doi: 10.1111/petr.14250. Epub 2022 Feb 10.

Abstract

BACKGROUND

The COVID-19 pandemic has affected medical care worldwide. Thus, we aimed to assess the impact of the COVID-19 pandemic on pediatric LT recipients.

METHODS

A cross-sectional study based on a structured internet or telephone survey was conducted among pediatric LT recipients. Survey results were compared with results of a survey conducted among pediatric patients with IBD.

RESULTS

Seventy-six pediatric LT patients participated in the study. Of them, 58 (76.3%) reported fear of severe COVID-19 infection due to LT or LT-associated medications. Half of the patients reported needing emotional support. Most patients (51, 67.1%) reported strictly following official guidance, while more stringent protective measures were taken by 64 (84.2%) patients. None of the patients discontinued their medications due to COVID-19. Compared to pediatric patients with IBD, a higher proportion of pediatric LT recipients reported fears of contracting severe COVID-19 infection due to their illness or medications (45, 59.2% vs. 110, 45.1%).

CONCLUSION

Among pediatric LT recipients a higher proportion reported fear of severe COVID-19 infection, implemented additional protective measures and expressed a need for emotional support, compared to patients with IBD. Medical teams should provide adequate information and offer a support system for this vulnerable population.

摘要

背景

COVID-19 大流行对全球医疗产生了影响。因此,我们旨在评估 COVID-19 大流行对儿科肝移植受者的影响。

方法

一项基于结构化互联网或电话调查的横断面研究在儿科肝移植受者中进行。调查结果与一项在儿科 IBD 患者中进行的调查结果进行了比较。

结果

76 名儿科肝移植患者参与了这项研究。其中,58 名(76.3%)因肝移植或肝移植相关药物而担心严重 COVID-19 感染。一半的患者报告需要情感支持。大多数患者(51 名,67.1%)严格遵循官方指南,而 64 名患者(84.2%)采取了更严格的保护措施。由于 COVID-19,没有患者停止用药。与 IBD 儿科患者相比,更多的儿科肝移植受者因疾病或药物而报告担心感染严重 COVID-19(45 名,59.2%比 110 名,45.1%)。

结论

与 IBD 患者相比,儿科肝移植受者中报告担心因疾病或药物而感染严重 COVID-19 的比例更高,实施了额外的保护措施,并表示需要情感支持。医疗团队应为这一弱势群体提供充分的信息和支持系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb9d/9115528/179ff1c06003/PETR-26-0-g001.jpg

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