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[肠系膜动脉缺血:从诊断到决策]

[Mesenteric arterial ischemia: from diagnosis to decision].

作者信息

Ben Abdallah Iannis, Castier Yves, Corcos Olivier

机构信息

Structure d'urgences vasculaires intestinales, APHP Nord, hôpitaux Beaujon-Bichat, université de Paris, France.

出版信息

Rev Prat. 2021 Oct;71(8):853-859.

Abstract

FROM DIAGNOSIS TO MULTIDISCIPLINARY TREATMENT IN INTESTINAL STOKE UNIT Acute mesenteric ischemia (AMI) is a severe vascular and intestinal emergency, most commonly related to the occlusion (mesenteric occlusive disease or emboli) of the superior mesenteric artery (SMA). Such as myocardial infarction or stroke, SMA occlusion is responsible of an intestinal infarction. In case of an early revascularization of the SMA, AMI can be reversible with no need for bowel resection. However, when left untreated, AMI fatally leads to irreversible intestinal necrosis and death following multiple organ failure. Considering its poor prognosis, AMI might be systematically suspected in case of a sudden, unusual and intense abdominal pain. Because AMI has a nonspecific clinical presentation, delayed diagnosis are frequent and unfortunately associated with poor outcomes. Therefore, general and emergency doctors, along with gastroenterologists, have a key role to play in the recognition of early AMI. In any case of clinically suspected AMI, an abdominal computed tomography angiogram might be urgently performed. Chronic mesenteric ischemia can also be revealed by postprandial abdominal pain associated with food fear and weight loss. In recent years, there has been a major improvement in the treatment of AMI following the creation of a French intestinal stroke center, gathering the expertise of specialized gastroentorologists, vascular and digestive surgeons, radiologists and intensivists. A multimodal and multidisciplinary approach combining the use of a systematic medical protocol, early revascularization of viable bowel and resection of non viable bowel when needed, has dramatically improved the prognosis of AMI, with current survival rates of 80 % and bowel resection being avoided in nearly two thirds of patients.

摘要

从肠道卒中单元的诊断到多学科治疗 急性肠系膜缺血(AMI)是一种严重的血管和肠道急症,最常见于肠系膜上动脉(SMA)闭塞(肠系膜闭塞性疾病或栓子)。与心肌梗死或中风一样,SMA闭塞会导致肠梗死。如果SMA能早期再血管化,AMI可能可逆,无需肠切除。然而,如果不治疗,AMI会致命地导致不可逆的肠坏死,并在多器官功能衰竭后死亡。鉴于其预后不良,在出现突发、异常且剧烈的腹痛时,可能应系统性怀疑AMI。由于AMI临床表现不具特异性,诊断延迟很常见,不幸的是其与不良预后相关。因此,普通科医生、急诊科医生以及胃肠病学家在早期AMI的识别中起着关键作用。在任何临床怀疑为AMI的情况下,可能需要紧急进行腹部计算机断层血管造影。慢性肠系膜缺血也可能表现为餐后腹痛伴惧食和体重减轻。近年来,随着法国肠道卒中中心的建立,AMI的治疗有了重大进展,该中心汇聚了专业胃肠病学家、血管和消化外科医生、放射科医生和重症监护医生的专业知识。一种多模式、多学科的方法,结合系统的医疗方案、对存活肠段的早期再血管化以及在需要时切除无活力的肠段,显著改善了AMI的预后,目前存活率为80%,近三分之二的患者避免了肠切除。

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