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复发性妊娠糖尿病:通过生活方式改变打破代际循环。

Recurrent gestational diabetes : Breaking the transgenerational cycle with lifestyle modification.

作者信息

Liney Thomas, Shah Nishel M, Singh Natasha

机构信息

The Hillingdon Hospitals NHS Foundation Trust, Pield Heath Road, UB8 3NN, Uxbridge, UK.

Imperial College London, Academic Department of Obstetrics & Gynaecology, Level 3, Chelsea and Westminster Hospital, 369 Fulham Road, SW10 9NH, London, UK.

出版信息

Wien Klin Wochenschr. 2022 Nov;134(21-22):788-798. doi: 10.1007/s00508-022-02004-3. Epub 2022 Feb 11.

Abstract

PURPOSE

This literature review is aimed at examining the benefits of lifestyle modifications in preventing recurrent gestational diabetes (GDM). Worldwide GDM affects approximately 16.2% of all pregnancies with significant maternal, fetal and neonatal complications. Almost two thirds of pregnant women with GDM will develop type 2 diabetes mellitus (T2DM) in the years following pregnancy. The proportion of women affected by GDM is on the rise and reflects increasing trends in T2DM as well as adult and childhood obesity.

METHODS

Using predefined subject headings, we searched for relevant articles from the PubMed, Scopus, and Cochrane databases.

RESULTS

For high-risk women lifestyle modifications, such as dietary and exercise changes, are the mainstay of treatment to reduce negative outcomes for both women and their pregnancies. This includes reducing the incidence of recurrent GDM and future T2DM by intervening during pregnancy and in the postnatal period.

CONCLUSION

This review provides an overview of the literature to date, discusses different targeted approaches and how these interventions can optimise their benefits, and where further research is required.

摘要

目的

本综述旨在探讨生活方式改变对预防复发性妊娠糖尿病(GDM)的益处。在全球范围内,GDM影响着约16.2%的妊娠,伴有严重的母婴及新生儿并发症。几乎三分之二的GDM孕妇在产后几年会发展为2型糖尿病(T2DM)。受GDM影响的女性比例呈上升趋势,这也反映出T2DM以及成人和儿童肥胖的增加趋势。

方法

我们使用预定义的主题词,在PubMed、Scopus和Cochrane数据库中检索相关文章。

结果

对于高危女性,生活方式的改变,如饮食和运动的调整,是减少女性及其妊娠不良结局的主要治疗方法。这包括通过在孕期和产后进行干预,降低复发性GDM和未来T2DM的发生率。

结论

本综述概述了迄今为止的文献,讨论了不同的针对性方法以及这些干预措施如何优化其益处,以及哪些方面需要进一步研究。

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