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极低出生体重儿喂养中使用混合巴氏杀菌母乳与未处理的母亲自身母乳的随机对照试验。

Pooled pasteurized breast milk and untreated own mother's milk in the feeding of very low birth weight babies: a randomized controlled trial.

作者信息

Stein H, Cohen D, Herman A A, Rissik J, Ellis U, Bolton K, Pettifor J, MacDougall L

出版信息

J Pediatr Gastroenterol Nutr. 1986 Mar-Apr;5(2):242-7.

PMID:3514832
Abstract

It has been shown that milk derived from mothers with term infants is not optimal for premature babies. There is also concern about the effect of heat sterilizing breast milk. At Baragwanath Hospital, the majority of mothers remain with and care for their premature babies. Over many years, pooled pasteurized breast milk has been fed to these babies before direct breast feeding is instituted. A study was done to compare feeding pooled pasteurized breast milk and untreated own mother's milk to very low birth weight babies. There was a significantly more rapid weight gain both in terms of regaining birth weight and, from this point, to reaching a weight of 1,800 g when using untreated own mother's milk. This occurred in spite of the fact that there was little difference, especially in terms of energy content, between the two types of breast milk. This was due to the fact that the pooled pasteurized milk was also largely obtained from mothers of premature babies. It is suggested from our data that slower weight gain in the group receiving the pooled pasteurized milk could be due to the pasteurization, which probably destroys heat-labile milk lipase.

摘要

研究表明,足月产婴儿母亲的乳汁对早产儿并非最佳选择。人们还担心母乳加热消毒的影响。在巴拉格瓦纳特医院,大多数母亲会陪伴并照顾自己的早产儿。多年来,在开始直接母乳喂养之前,一直用混合巴氏杀菌母乳喂养这些婴儿。开展了一项研究,比较用混合巴氏杀菌母乳和未处理的母亲自己的母乳喂养极低出生体重婴儿的情况。使用未处理的母亲自己的母乳时,无论在恢复出生体重方面,还是从这一点开始到达到1800克体重方面,体重增加都明显更快。尽管两种母乳之间差异不大,尤其是在能量含量方面,但仍出现了这种情况。这是因为混合巴氏杀菌母乳也主要取自早产儿的母亲。从我们的数据来看,接受混合巴氏杀菌母乳的组体重增加较慢可能是由于巴氏杀菌,这可能破坏了热不稳定的乳脂肪酶。

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