Lee Tsz Kin, Wibowo Erik, Dowsett Gary W, Nelson Christian J, Oliffe John L, Mitteldorf Darryl, Wong Samantha Tze Sum, Wassersug Richard J
Radiation Oncology, British Columbia Cancer, Abbotsford Cancer Centre, British Columbia, Canada.
Department of Anatomy, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Sex Med. 2022 Apr;10(2):100480. doi: 10.1016/j.esxm.2021.100480. Epub 2022 Feb 8.
Prostate cancer (PCa) is often diagnosed early with prolonged survival, which makes sexual quality of life (QoL) an increasingly important treatment consideration, but existing QoL questionnaires have limited applicability for men who-have-sex-with-men (MSM) beyond penile erections and penetrative sex.
We aimed to create a validated survey instrument for assessing a variety of sexual activities beyond penile insertive sex for MSM after PCa treatment.
Based on our previously published survey findings, we have generated a prototype questionnaire with 13 different domains, reviewed by both healthy MSM and pilot-tested by MSM treated for PCa.
We report here on progress in developing the questionnaire and demonstrate the complexity of MSM sexual side effects resulting from PCa treatment(s).
Statistical analysis of 204 responses from MSM treated for PCa showed that each domain performed well individually (Cronbach's alpha coefficients ranged from 0.80 to 0.95; item-total correlations ranged from 0.16 to 0.89), with many significant intercorrelations between the domains (ranged from -0.048 to 0.93).
The questionnaire can contribute to clinical diagnosis and treatment decisions that best fit the preferred sexual practices of individual MSM.
STRENGTHS & LIMITATIONS: The current questionnaire considers a much broader repertoire of MSM's sexual practices and preferences than other currently available questionnaires. The high intercorrelations between the many parameters demonstrate that problems in one domain can affect other domains. This preliminary analysis warrants further exploration with a larger sample size.
Once validated our questionnaire should help develop tailored psychosocial supports for MSM experiencing sexual dysfunction after PCa treatment and help newly diagnosed MSM with PCa make treatment decisions informed by their preferred sexual practices. Wibowo E, Dowsett GW, Nelson CJ, et al. Development of a Sexual Quality of Life Questionnaire for Men-Who-Have-Sex-With-Men With Prostate Cancer. Sex Med 2022;10:100480.
前列腺癌（PCa）通常能早期诊断且生存期延长，这使得性生活质量（QoL）成为治疗中越来越重要的考量因素，但现有的QoL问卷对于男男性行为者（MSM）而言，除阴茎勃起和插入式性行为外，适用性有限。
我们旨在创建一种经过验证的调查工具，用于评估PCa治疗后MSM除阴茎插入式性行为之外的各种性活动。
基于我们之前发表的调查结果，我们生成了一份包含13个不同领域的原型问卷，由健康的MSM进行评审，并由接受PCa治疗的MSM进行预测试。
我们在此报告问卷开发的进展情况，并展示PCa治疗导致的MSM性副作用的复杂性。
对204名接受PCa治疗的MSM的回复进行统计分析表明，每个领域单独表现良好（克朗巴哈系数范围为0.80至0.95；项目与总分的相关性范围为0.16至0.89），各领域之间存在许多显著的相互关联（范围为-0.048至0.93）。
该问卷有助于做出最适合个体MSM偏好性行为的临床诊断和治疗决策。
当前问卷考虑的MSM性行为和偏好范围比其他现有问卷广泛得多。许多参数之间的高度相互关联表明，一个领域的问题可能会影响其他领域。这一初步分析需要用更大的样本量进行进一步探索。
一旦经过验证，我们的问卷应有助于为PCa治疗后出现性功能障碍的MSM制定量身定制的心理社会支持措施，并帮助新诊断出PCa的MSM根据其偏好的性行为做出治疗决策。维博沃E、道塞特GW、纳尔逊CJ等。为患有前列腺癌的男男性行为者开发性生活质量问卷。性医学2022；10：100480。
