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临床观察瘢痕疙瘩患者皮下血管网皮瓣。

Clinical Observation of Subepidermal Vascular Network Flaps in Keloid Patients.

机构信息

Department of Plastic Surgery, Peking Union Medical College Hospital, No. 41 Damucang Hutong, Xicheng District, Beijing, China.

Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

出版信息

Aesthetic Plast Surg. 2022 Aug;46(4):2015-2022. doi: 10.1007/s00266-022-02783-0. Epub 2022 Feb 11.

Abstract

BACKGROUND

There are many different keloid treatment modalities. One surgical technique is to keep the "shell" of the keloid to cover the defect. We named this "shell" keloid subepidermal vascular network flap (KSVNF), and we outlined the characteristics of this flap by observing 35 flaps in keloid patients.

METHODS

A total of 35 KSVNFs were designed in 15 patients during 2020-2021. All patients underwent the operation and adjuvant radiotherapy as well as hyperbaric oxygen therapy. All flap lengths and widths were recorded, and the blood perfusion of the flaps was measured on the first day postoperation and the day of stitch removal. Flap survival and the quality of flaps were evaluated on the day of stitch removal. All harvested data were analyzed using the R (version 4.0.1) package.

RESULTS

The mean blood perfusion on the first day postoperation (pod1) and the day of stitch removal was 120.4013 and 168.6900, respectively (p = 0.02249); 2 flaps had partial necrosis (5.714%). Receiver operating characteristic (ROC) curve analysis showed that when the length/width ratio was less than 1.05, the quality of the flap was good (AUC = 0.724), which suggests that the effective safe length/width ratio was 1.05.

CONCLUSION

KSVNF is an applicable method for covering the remaining wound after keloid mass removal with sufficient blood perfusion and adequate skin quality. We recommend that the length/width ratio of the flap design not exceed 1.

LEVEL OF EVIDENCE IV

This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

摘要

背景

有许多不同的瘢痕疙瘩治疗方法。一种手术技术是保留瘢痕疙瘩的“外壳”来覆盖缺损。我们将这种“外壳”称为瘢痕下表皮血管网皮瓣(KSVNF),并通过观察 35 例瘢痕疙瘩患者的皮瓣来描述这种皮瓣的特征。

方法

2020 年至 2021 年期间,15 名患者共设计了 35 个 KSVNF。所有患者均接受手术、辅助放疗和高压氧治疗。记录所有皮瓣的长度和宽度,并在术后第 1 天和拆线当天测量皮瓣的血液灌注情况。在拆线当天评估皮瓣的存活率和质量。使用 R(版本 4.0.1)包分析所有采集的数据。

结果

术后第 1 天(pod1)和拆线当天的平均血流灌注分别为 120.4013 和 168.6900(p=0.02249);2 个皮瓣部分坏死(5.714%)。受试者工作特征(ROC)曲线分析表明,当长宽比小于 1.05 时,皮瓣质量良好(AUC=0.724),提示有效安全的长宽比为 1.05。

结论

KSVNF 是一种适用于切除瘢痕疙瘩肿块后覆盖剩余伤口的方法,具有充足的血液灌注和足够的皮肤质量。我们建议皮瓣设计的长宽比不超过 1。

证据等级 IV:本杂志要求作者为每个提交的稿件分配一个证据等级,这些等级适用于循证医学的排名。这排除了综述文章、书评以及涉及基础科学、动物研究、尸体研究和实验研究的手稿。有关这些循证医学等级的完整描述,请参阅目录或在线作者指南 www.springer.com/00266

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