费城染色体阳性急性淋巴细胞白血病的异基因骨髓移植
Allogeneic bone marrow transplantation for Philadelphia-chromosome positive acute lymphoblastic leukemia.
作者信息
Reece D E, Buskard N A, Hill R S, Fryer C J, Naiman S C, Phillips G L
出版信息
Leuk Res. 1986;10(4):457-9. doi: 10.1016/0145-2126(86)90077-9.
PMID:3515055
Abstract
Allogeneic bone marrow transplantation (BMT) produced remission in three patients with Philadelphia-chromosome (Ph1)-positive acute lymphoblastic leukemia (ALL) in relapse. Two patients had remissions which lasted longer than two years. Since the prognosis of Ph1-positive ALL treated with conventional therapy is poor, BMT is indicated in first remission in this disease.
摘要
异基因骨髓移植（BMT）使3例复发的费城染色体（Ph1）阳性急性淋巴细胞白血病（ALL）患者获得缓解。2例患者的缓解期持续超过两年。由于采用传统疗法治疗Ph1阳性ALL的预后较差，因此该病首次缓解时即应进行BMT。
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