Baskent University, Department of General Surgery, Ankara, Turkey.
Baskent University, Department of General Surgery, Division of Transplantation, Ankara, Turkey.
Am J Emerg Med. 2022 Apr;54:142-146. doi: 10.1016/j.ajem.2022.01.034. Epub 2022 Feb 3.
It is important to distinguish between complicated acute appendicitis (CAA) and noncomplicated acute appendicitis (NCAA) because the treatment methods are different. We aimed to create an algorithm that determines the severity of acute appendicitis (AA) without the need for imaging methods, using the decision tree method.
The patients were analyzed retrospectively and divided into two groups as CAA and NCAA. Age, gender, Alvarado scores, white blood cell values (WBC), neutrophil/lymphocyte ratios (NLR), C-reactive protein value (CRP), albumin value and CRP/Albumin ratios of the patients were recorded.
In the algorithm we created, the most important parameter in the distinction between CAA and NCAA is CRP. NLR is predictive in patients with a CRP value of ≤107.565 mg/L, and the critical value is NLR 2.165. In patients with a CRP value of >107.565 mg/L, albumin is the determinant and the critical value is 2.85 g/dL. Age, gender, alvarado score and CRP/albumin ratio have no significance in distinguishing between CAA and NCAA. In the statistical analysis, there were significant differences between NCAA and CAA groups in terms of age (39.56 years vs 13,675 years), gender (48.1% male vs 71.4% male), WBC (13,891.10/mL vs 11,614.76/mL), CRP (27 mg/L vs 127 mg/L), albumin (3 g/dL vs 3 g/dL) and CRP/albumin (9.50 vs. 41).
Thanks to the algorithm we created, CAA and NCAA distinction can be made quickly. In addition, by avoiding unnecessary surgical procedures in NCAA cases, patients' quality of life can be increased and morbidity rates can be minimized.
区分复杂型急性阑尾炎(CAA)和非复杂型急性阑尾炎(NCAA)很重要,因为治疗方法不同。我们旨在创建一种无需使用影像学方法即可确定急性阑尾炎(AA)严重程度的算法,使用决策树方法。
回顾性分析患者,分为 CAA 和 NCAA 两组。记录患者的年龄、性别、Alvarado 评分、白细胞计数(WBC)、中性粒细胞/淋巴细胞比值(NLR)、C 反应蛋白值(CRP)、白蛋白值和 CRP/白蛋白比值。
在我们创建的算法中,区分 CAA 和 NCAA 的最重要参数是 CRP。在 CRP 值≤107.565mg/L 的患者中,NLR 具有预测性,临界值为 NLR 2.165。在 CRP 值>107.565mg/L 的患者中,白蛋白是决定因素,临界值为 2.85g/dL。年龄、性别、Alvarado 评分和 CRP/白蛋白比值在区分 CAA 和 NCAA 方面无意义。在统计分析中,NCAA 和 CAA 组在年龄(39.56 岁比 13.675 岁)、性别(48.1%男性比 71.4%男性)、WBC(13891.10/mL 比 11614.76/mL)、CRP(27mg/L 比 127mg/L)、白蛋白(3g/dL 比 3g/dL)和 CRP/白蛋白(9.50 比 41)方面存在显著差异。
多亏了我们创建的算法,可以快速区分 CAA 和 NCAA。此外,通过避免 NCAA 病例中不必要的手术,可以提高患者的生活质量并最大限度地降低发病率。