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使用智能手机进行脊髓型颈椎病的临床评估:一项可行性研究

Using Smartphones for Clinical Assessment in Cervical Spondylotic Myelopathy a Feasibility Study.

作者信息

Zaldivar-Jolissaint Julien Francisco, Lechanoine François, Krummenacher Bernard, Arruda Rivus Ferreira, Bobinski Lukas, de Schlichting Emmanuel, Duff John Michael

机构信息

Service de Neurochirurgie, Centre Hospitalier Universitaire de Grenoble-Alpes, Grenoble 38000, France.

Independent Service Provider, Silicon-Peace, Renens 1020, Switzerland.

出版信息

J Med Device. 2021 Dec 1;15(4):044503. doi: 10.1115/1.4052609. Epub 2021 Oct 22.

Abstract

Degenerative cervical myelopathy (DCM) is characterized by a progressive deterioration in spinal cord function. Its evaluation requires subjective clinical examination with wide interobserver variability. Objective quantification of spinal cord function remains imprecise, even though validated myelopathy-grading scales have emerged and are now widely used. We created a Smartphone Application, the N-Outcome App, with the aim of quantifying accurately and reliably spinal cord dysfunction using a 5-minute Test. A patient suffering from DCM was clinically evaluated before surgery, at 3 and 6 months follow-up after surgical decompression of the cervical spinal cord. Standard scores (Nurick grade, modified Japanese Orthopedic Association (mJOA) score) were documented at these time points. A 5-minute motor and proprioceptive performance test aided by a smartphone with the N-outcome App was also performed. Motor performance in rapid alternating movements and finger tapping improved in correlation with improvements in standard grading scale scores. Clinical improvements were seen in maximum reflex acceleration and in Romberg testing which showed less closed/open eyes variation, suggesting pyramidal and proprioceptive function recovery. We demonstrate that using the N-Outcome App as an adjunct to clinical evaluation of compressive myelopathy is feasible and potentially useful. The results correlate with the results of clinical assessment obtained by standard validated myelopathy scores.

摘要

退行性颈椎病性脊髓病(DCM)的特征是脊髓功能逐渐恶化。对其进行评估需要进行主观的临床检查,不同观察者之间的差异较大。尽管已经出现并广泛使用了经过验证的脊髓病分级量表,但脊髓功能的客观量化仍然不够精确。我们创建了一款智能手机应用程序——N-Outcome应用程序,旨在通过一项5分钟的测试准确、可靠地量化脊髓功能障碍。一名患有DCM的患者在手术前、颈椎脊髓减压术后3个月和6个月随访时接受了临床评估。在这些时间点记录了标准评分(努里克分级、改良日本骨科学会(mJOA)评分)。还进行了一项由配备N-Outcome应用程序的智能手机辅助的5分钟运动和本体感觉性能测试。快速交替运动和手指敲击的运动性能与标准分级量表评分的改善相关。在最大反射加速度和罗姆伯格测试中观察到临床改善,表现为闭眼/睁眼差异减小,提示锥体束和本体感觉功能恢复。我们证明,将N-Outcome应用程序作为压迫性脊髓病临床评估的辅助手段是可行的,且可能有用。其结果与通过标准验证的脊髓病评分获得的临床评估结果相关。

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