肠道微生物群、血管紧张素转换酶、乳糜泻与新型冠状病毒肺炎感染风险：综述
Gut microbiota, angiotensin-converting enzyme, celiac disease, and risk of COVID-19 infection: a review.
作者信息
Gholam-Mostafaei Fahimeh Sadat, Didari Tina, Ramandi Marzieh, Vafaee Reza, Rostami-Nejad Mohammad
机构信息
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pharmaceutical Products Technology Development Center, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Gastroenterol Hepatol Bed Bench. 2021 Fall;14(Suppl1):S24-S31.
Celiac disease (CD) is an autoimmune disorder of the gastrointestinal tract in a genetically susceptible person. Gluten is the most crucial trigger factor for CD, and environmental factors such as microbiota and opportunistic infection risk its pathogenesis. Coronavirus disease 19 (COVID-19) spread rapidly and became a problem for healthcare systems worldwide. Little is known about the risk of severe COVID-19 and the role of dysbiosis among patients with CD. There is also a lack of knowledge about the effects of CD gut microbiota on COVID-19 infection. Therefore, the current review discusses the relationship between CD and risk factors such as microbiota for susceptibility to COVID-19.
乳糜泻（CD）是一种发生在基因易感性个体中的胃肠道自身免疫性疾病。麸质是CD最关键的触发因素，微生物群和机会性感染等环境因素影响其发病机制。2019冠状病毒病（COVID-19）迅速传播，成为全球医疗系统面临的一个问题。关于重症COVID-19的风险以及CD患者中生态失调的作用，人们知之甚少。对于CD肠道微生物群对COVID-19感染的影响也缺乏了解。因此，本综述讨论了CD与微生物群等COVID-19易感性风险因素之间的关系。
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