Allameh Farzad, Razzaghi Mohammadreza, Hosseini Sedighe, Barati Maryam, Razzaghi Zahra, Salehi Safa, Ghahestani Seyed Mohammad, Shahabi Vahid
Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Infertility & IVF, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Lasers Med Sci. 2021 Dec 27;12:e84. doi: 10.34172/jlms.2021.84. eCollection 2021.
Currently, infertility is a main concern, and it is estimated that 15% of couples are considered infertile. Conventional therapies such as vitamins, antioxidants and supplements have been used widely, but they may not be sufficiently effective. This study evaluated the effect of laser acupuncture on semen parameters in infertile patients with oligospermia. This study is a clinical trial with a double-blind control group. 35 patients in the intervention group underwent laser acupuncture twice a week for consecutive 5-weeks. In the control group, sham laser acupuncture was performed. The two groups were compared in terms of semen parameters including semen volume, sperm concentration, sperm motility and sperm morphology as the primary outcome. The secondary outcome was a successful pregnancy rate. After data collection, statistical analysis was performed with SPSS version 20. The mean age of all patients was 27.46±2.88 years; in the intervention group, their age was 27.82±2.6 years, and in the control group, it was 27.11±2.96 years, and there was no significant difference (=0.396). During the study, 4 patients (5.4%) reported adverse effects; three patients in the control group complained of mild weakness and itching, and one patient in the intervention group reported dizziness. The volume of semen and sperm morphology did not differ significantly in both control and intervention groups ( ˃ 0.05), while sperm motility and sperm concentration had a significant difference (=0.0001). Laser acupuncture as a non-invasive procedure is effective in improving sperm mobility and concentration in infertile patients with oligospermia. Due to the surface contact of the laser probe with the skin and the lack of need to insert needles in the skin, laser acupuncture is more convenient and better tolerated by patients.
目前，不孕症是一个主要问题，据估计15%的夫妇被认为患有不孕症。维生素、抗氧化剂和补充剂等传统疗法已被广泛使用，但它们可能效果不够显著。本研究评估了激光针灸对少精子症不育患者精液参数的影响。本研究是一项设有双盲对照组的临床试验。干预组的35名患者连续5周每周接受两次激光针灸治疗。对照组则进行假激光针灸治疗。比较两组的精液参数，包括精液量、精子浓度、精子活力和精子形态作为主要结果。次要结果是成功怀孕率。收集数据后，使用SPSS 20版进行统计分析。所有患者的平均年龄为27.46±2.88岁；干预组患者年龄为27.82±2.6岁，对照组为27.11±2.96岁，差异无统计学意义（=0.396）。在研究过程中，4名患者（5.4%）报告了不良反应；对照组的3名患者抱怨有轻微的虚弱和瘙痒，干预组的1名患者报告有头晕。对照组和干预组的精液量和精子形态差异均无统计学意义（˃0.05），而精子活力和精子浓度有显著差异（=0.0001）。激光针灸作为一种非侵入性程序，对改善少精子症不育患者的精子活力和浓度有效。由于激光探头与皮肤表面接触，无需将针插入皮肤，激光针灸更方便，患者耐受性更好。
