Heo Jae Sung, Gil Dongkyun, Kim Cheal
Department of Fine Chemistry and Renewable Energy Convergence, SNUT (Seoul National University of Science and Technology), Seoul, South Korea.
Luminescence. 2022 May;37(5):684-690. doi: 10.1002/bio.4209. Epub 2022 Feb 23.
We designed a thiophene-based fluorescent chemosensor DHTC ((E)-2-([3,5-dichloro-2-hydroxybenzylidene]amino)thiophene-3-carboxamide) for detecting gallium (Ga ). DHTC could probe Ga using fluorescence enhancement. The limit of detection for Ga by DHTC was 0.39 μM. The binding mode of DHTC to Ga was determined as a 1:1 ratio from analysis by Job's plot and electrospray ionization-mass spectrometry (ESI-MS). In addition, DHTC could selectively detect Ga using test kits. The sensing process of Ga by DHTC was presented using ultraviolet-visible light titration, Job's plot, ESI-MS, H nuclear magnetic resonance titration, and density functional theory calculation.
我们设计了一种基于噻吩的荧光化学传感器DHTC（（E）-2-（[3,5-二氯-2-羟基亚苄基]氨基）噻吩-3-甲酰胺）用于检测镓（Ga）。DHTC可通过荧光增强来探测Ga。DHTC对Ga的检测限为0.39μM。通过Job曲线和电喷雾电离质谱（ESI-MS）分析确定DHTC与Ga的结合模式为1:1比例。此外，DHTC可使用测试试剂盒选择性地检测Ga。通过紫外-可见光滴定、Job曲线、ESI-MS、氢核磁共振滴定和密度泛函理论计算展示了DHTC对Ga的传感过程。
