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iPTH is not a significant factor influencing the tacrolimus C/D ratio.

作者信息

Westphal Florian, Jehn Ulrich, Görlich Dennis, Reuter Stefan

机构信息

Department of Medicine D, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital Münster, Münster, Germany.

Institute of Biostatistics and Clinical Research, University Hospital Münster, Münster, Germany.

出版信息

Clin Transl Sci. 2022 Apr;15(4):805-806. doi: 10.1111/cts.13245. Epub 2022 Feb 14.

DOI:10.1111/cts.13245
PMID:35157352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9010258/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecc2/9010258/164b39a86ecb/CTS-15-805-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecc2/9010258/164b39a86ecb/CTS-15-805-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecc2/9010258/164b39a86ecb/CTS-15-805-g001.jpg

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本文引用的文献

1
Association of CYP3A5 polymorphisms and parathyroid hormone with blood level of tacrolimus in patients with end-stage renal disease.CYP3A5 多态性与甲状旁腺激素与终末期肾病患者他克莫司血药浓度的关系。
Clin Transl Sci. 2021 Sep;14(5):2034-2042. doi: 10.1111/cts.13065. Epub 2021 May 31.
2
Effect of Serum Parathyroid Hormone on Tacrolimus Therapy in Kidney Transplant Patients: A Possible Biomarker for a Tacrolimus Dosage Schedule.甲状旁腺激素对肾移植患者他克莫司治疗的影响：他克莫司剂量方案的一个可能生物标志物。
Biol Pharm Bull. 2019;42(5):786-791. doi: 10.1248/bpb.b18-00976.
3
Factors involved in phenoconversion of CYP3A using 4β-hydroxycholesterol in stable kidney transplant recipients.
在稳定的肾移植受者中，使用 4β-羟胆固醇导致 CYP3A 表型转化的相关因素。
Pharmacol Rep. 2019 Apr;71(2):276-281. doi: 10.1016/j.pharep.2018.12.007. Epub 2018 Dec 15.
4
Tacrolimus - Pharmacokinetic Considerations for Clinicians.他克莫司——临床医生的药代动力学考量
Curr Drug Metab. 2018;19(4):342-350. doi: 10.2174/1389200219666180101104159.
5
Parathyroid hormone contributes to the down-regulation of cytochrome P450 3A through the cAMP/PI3K/PKC/PKA/NF-κB signaling pathway in secondary hyperparathyroidism.甲状旁腺激素通过环磷酸腺苷/磷脂酰肌醇-3激酶/蛋白激酶C/蛋白激酶A/核因子κB信号通路，参与继发性甲状旁腺功能亢进时细胞色素P450 3A的下调过程。
Biochem Pharmacol. 2017 Dec 1;145:192-201. doi: 10.1016/j.bcp.2017.08.016. Epub 2017 Aug 24.