Section of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.
Department of Surgery, Section of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.
J Pak Med Assoc. 2021 Jan;71(1(B)):385-387.
Glioblastoma is rather uncommon in children, accounting for less than 5% of all paediatric brain tumours. Recent large sample size cohorts have clearly shown that extent of resection and adjuvant chemotherapy and radiotherapy impact survival. Unfortunately, this may not be the practice in a real world setting, especially in low-middle income countries (LMIC). The aim of this review is to summarize and highlight important findings from studies on paediatric glioblastoma.
胶质母细胞瘤在儿童中较为罕见,占所有儿童脑肿瘤的比例不到 5%。最近的大样本队列研究清楚地表明,切除范围以及辅助化疗和放疗对生存有影响。不幸的是,在现实环境中,这可能并非惯例,尤其是在中低收入国家(LMIC)。本综述的目的是总结和强调关于儿童胶质母细胞瘤的研究中的重要发现。