Department of Chemistry and Pharmacy, Friedrich-Alexander Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany.
Department of Chemistry and Center for Integrated Protein Science (CIPSM), Ludwig-Maximilians Universität München, Butenandtstr. 5-13, 81377 Munich, Germany.
J Am Chem Soc. 2022 Feb 23;144(7):2847-2852. doi: 10.1021/jacs.1c12364. Epub 2022 Feb 14.
Molecular photoswitches that offer simultaneous precise control over geometrical and electronic changes are rare yet highly sought tools for the development of responsive nanosystems. Here we present such an advantageous combination of property control within a novel multiphotoswitch architecture. Hemithioindigo-based trioxobicyclononadiene (HTI-TOND) offers a rigid three-dimensional molecular structure that undergoes different exotic rearrangement reactions upon photochemical and thermal signaling. Three to four different states with distinct geometric and electronic properties can be accessed reversibly in high yields within this molecular framework. Thus, a highly promising and unique switching tool has become available to instill the next level of addressability at the smallest scales.
同时提供对几何形状和电子变化进行精确控制的分子光开关非常罕见，但对于开发响应性纳米系统而言，它们是高度需要的工具。在这里，我们在一种新颖的多光开关结构中展示了这种有利的特性控制组合。基于半硫靛的三氧杂双环壬二烯（HTI-TOND）提供了刚性的三维分子结构，在光化学和热信号作用下会发生不同的奇特重排反应。在这个分子框架内，可以以高收率可逆地进入三种到四种具有不同几何形状和电子特性的不同状态。因此，一种非常有前途和独特的开关工具已经可用，为最小尺度上的下一层次的寻址能力提供了可能。
