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肾上腺血肿与合并出血的神经母细胞瘤。新生儿中的诊断难题。

Suprarenal haematoma versus neuroblastoma complicated by haemorrhage. A diagnostic dilemma in the newborn.

作者信息

Eklöf O, Mortensson W, Sandstedt B

出版信息

Acta Radiol Diagn (Stockh). 1986 Jan-Feb;27(1):3-10. doi: 10.1177/028418518602700102.

Abstract

Concomitant neonatal suprarenal haemorrhage and neuroblastoma is rare. The clinical and radiologic manifestations recorded in 11 patients with this entity are compared with the findings in 32 cases with simple adrenal haemorrhage. Because of the many similarities in presentation the combined lesion must always be considered when a neonate is found to have a retroperitoneal, extra-renal mass. Our present approach to the investigation includes conventional chest and abdominal radiography aimed to demonstrate possible paravertebral widening. Serial ultrasonographies are easy to carry out and indispensable. The low specificity of urography makes us refrain from this modality as a routine. Scintigraphy, in infants and children considered useful in demonstrating extent and spread of neuroblastoma, has hardly been employed in neonates. The true value of the modality in this particular age group remains to be settled. CT scanning does not seem to provide essential information additional to that of sonography and may therefore be excluded from the protocol. Determination of urinary excretion of catecholamine metabolites is of crucial significance and a compulsory part of the investigation.

摘要

新生儿肾上腺出血合并神经母细胞瘤较为罕见。将11例患有该病症的患者的临床和放射学表现与32例单纯肾上腺出血患者的检查结果进行了比较。由于临床表现存在诸多相似之处,因此当发现新生儿有腹膜后肾外肿块时,必须始终考虑到合并病变的可能性。我们目前的检查方法包括常规胸部和腹部X线摄影,旨在显示可能的椎旁增宽。连续超声检查操作简便且必不可少。尿路造影的低特异性使我们不再将其作为常规检查手段。闪烁扫描在婴幼儿中被认为有助于显示神经母细胞瘤的范围和扩散情况,但在新生儿中几乎未被采用。该检查方法在这一特定年龄组中的真正价值仍有待确定。CT扫描似乎并不能提供比超声检查更多的重要信息,因此可以从检查方案中排除。测定儿茶酚胺代谢产物的尿排泄量至关重要,是检查的必要组成部分。

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