Abd Ziad H, Muter Samir A
Department of Surgery, College of Medicine, University of Anbar, Ramadi 31001, Iraq.
Department of Surgery, College of Medicine, University of Baghdad, Baghdad 10001, Iraq.
J Clin Med. 2022 Jan 20;11(3):513. doi: 10.3390/jcm11030513.
This study aimed to compare the safety and efficacy of laser lithotripsy and pneumatic lithotripsy, the two most commonly used transurethral lithotripsy methods for treating bladder stones in children in Iraq. Between January 2013 and December 2016, 64 children with bladder stones were included in this prospective randomized study, after ethical committee approval and written consent from the children's parents or caregivers were obtained. Patients were assigned randomly by computer software to two groups treated with either pneumatic cystolithotripsy or laser lithotripsy. A 9 Fr. semirigid ureteroscope was used to pass the lithotripter through and fragment the stone. A catheter of 8-12 Fr. was then introduced and kept in place for 24 h. All children were hospitalized for 24 h, and the catheter was removed the next morning. Outpatient follow-up was maintained for 6-12 months. In terms of operation outcomes and complications, the laser lithotripsy group had a significantly longer duration of operation (74.5 ± 26.6 min vs. 51.5 ± 17.2 min, = 0.001), whereas the number of patients requiring an extended hospital stay was significantly higher in the pneumatic lithotripsy group (48.5% vs. 16.1%, = 0.006). Moreover, pneumatic lithotripsy was associated with a significantly greater risk of having at least one adverse effect (64% greater than that in the laser group). Stone clearance rates did not significantly differ between treatment groups. In conclusion, both pneumatic and laser lithotripters can be used to treat children with bladder stones with high efficacy and safety.
本研究旨在比较激光碎石术和气压弹道碎石术这两种伊拉克治疗儿童膀胱结石最常用的经尿道碎石方法的安全性和有效性。在获得伦理委员会批准以及儿童父母或监护人的书面同意后,于2013年1月至2016年12月期间,64例膀胱结石患儿被纳入这项前瞻性随机研究。患者通过计算机软件随机分为两组,分别接受气压弹道碎石术或激光碎石术治疗。使用9 Fr.半硬性输尿管镜将碎石器通过并粉碎结石。然后插入一根8 - 12 Fr.的导管并留置24小时。所有儿童均住院24小时,次日早晨拔除导管。进行6 - 12个月的门诊随访。在手术结果和并发症方面,激光碎石术组的手术时间明显更长(74.5 ± 26.6分钟对51.5 ± 17.2分钟,P = 0.001),而气压弹道碎石术组需要延长住院时间的患者数量明显更高(48.5%对16.1%,P = 0.006)。此外,气压弹道碎石术出现至少一种不良反应的风险明显更高(比激光组高64%)。治疗组之间的结石清除率没有显著差异。总之,气压弹道碎石术和激光碎石术均可用于高效安全地治疗儿童膀胱结石。