Ferreira-Cendon Sofía, Martinez-Carranza Ramon, Fernandez-Nava Maria José, Villaoslada-Fuente Rosana, Sanchez-Gomez Hortensia, Santa Cruz-Ruiz Santiago, Sanchez-Ledesma María, Batuecas-Caletrio Angel
Neurotology Unit, ENT Department, University Hospital of Salamanca, IBSAL, 37007 Salamanca, Spain.
Neurotology Unit, ENT Department, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain.
J Clin Med. 2022 Jan 25;11(3):586. doi: 10.3390/jcm11030586.
The importance of early evaluation by a neurotologist in patients with infective endocarditis treated with systemic gentamicin and its impact on the patients' quality of life was evaluated. This is a longitudinal retrospective cohort study of 29 patients who received intravenous gentamicin for the treatment of infective endocarditis. Patients were classified into two groups: group A, before a neurotologist was included in the treatment protocol, and group B, after the inclusion of a neurotologist. The frequency of the different symptoms in each group was measured, and the gain of the vestibulo-ocular reflex (VOR) and its relationship with the presence of oscillopsia. In total, 13 and 16 patients were assigned to groups A and B, respectively. The mean gain of the VOR measured using the video head impulse test in group A was 0.44 in the best side and 0.39 in the worst side. In group B, the mean gain was 0.71 (best side) and 0.64 (worst side) ( < 0.0001). The patients who complained about oscillopsia had a main gain of 0.41 in the best side and 0.35 in the worst side. Evaluation of vestibular function should be included in the infective endocarditis treatment protocol, including the adverse effects of systemic gentamicin.
评估了耳神经科医生对接受全身庆大霉素治疗的感染性心内膜炎患者进行早期评估的重要性及其对患者生活质量的影响。这是一项对29例接受静脉注射庆大霉素治疗感染性心内膜炎患者的纵向回顾性队列研究。患者分为两组：A组，治疗方案中未纳入耳神经科医生之前；B组，纳入耳神经科医生之后。测量了每组中不同症状的发生频率，以及前庭眼反射（VOR）的增益及其与视振荡的关系。总共分别有13例和16例患者被分配到A组和B组。A组使用视频头脉冲测试测量的VOR平均增益，最佳侧为0.44，最差侧为0.39。B组的平均增益为0.71（最佳侧）和0.64（最差侧）（<0.0001）。抱怨视振荡的患者，最佳侧的主要增益为0.41，最差侧为0.35。感染性心内膜炎治疗方案应包括前庭功能评估，包括全身庆大霉素的不良反应。
