Timm Karsten, Walter Nike, Heinrich Martin, Knapp Gero, Thormann Ulrich, El Khassawna Thaqif, Alt Volker, Heiss Christian, Rupp Markus
Department of Trauma, Hand and Reconstructive Surgery, University Hospital Giessen GmbH, 35392 Giessen, Germany.
Department of Trauma Surgery, University Hospital Regensburg, 93053 Regensburg, Germany.
J Clin Med. 2022 Jan 28;11(3):717. doi: 10.3390/jcm11030717.
Pre-clinical studies indicate that concomitant thoracic trauma impairs fracture healing of long bones and reduces callus formation. The aim of this study was to investigate whether patients with accompanying chest trauma suffer from delayed fracture healing of long bones in comparison with patients with fractures of two long bones or isolated fractures.
This is a clinical retrospective study from a level I trauma center. The patients were divided into three groups: (1) thoracic trauma and fracture of a long bone, (2) fractures of two long bones, (3) isolated fracture of a long bone. The fracture consolidation was defined using the radiographic union scale in tibial fractures (RUST). A RUST value of ≥10 six-to-eight months after definitive operative intervention represented complete fracture healing.
In the first group 19 (43.2%) fractures did not show full consolidation, in the second group 14 (45.2%) and 13 (41.9%) and in the third group 14 (36.8%). The analysis revealed no statistically significant differences between the groups regarding consolidation of the fractures six-to-eight months after definitive operative intervention ( = 0.84).
Unlike previously reported pre-clinical data, this study did not demonstrate a negative effect on fracture consolidation in long bones when accompanied by thoracic trauma. Furthermore, the results demonstrated that concomitant fractures of two long bones does not have a negative effect on fracture consolidation.
临床前研究表明，合并胸部创伤会损害长骨骨折愈合并减少骨痂形成。本研究的目的是调查与两根长骨骨折或孤立骨折患者相比，伴有胸部创伤的患者是否存在长骨骨折愈合延迟的情况。
这是一项来自一级创伤中心的临床回顾性研究。患者被分为三组：（1）胸部创伤合并长骨骨折，（2）两根长骨骨折，（3）孤立的长骨骨折。使用胫骨骨折的放射学愈合量表（RUST）定义骨折愈合情况。在确定性手术干预后六至八个月，RUST值≥10代表骨折完全愈合。
第一组中19例（43.2%）骨折未完全愈合，第二组中14例（45.2%）和13例（41.9%），第三组中14例（36.8%）。分析显示，在确定性手术干预后六至八个月，各组之间骨折愈合情况无统计学显著差异（=0.84）。
与先前报道的临床前数据不同，本研究未证明胸部创伤伴有长骨骨折时对骨折愈合有负面影响。此外，结果表明两根长骨合并骨折对骨折愈合无负面影响。
