Patterson R, Greenberger P A, Halwig J M, Liotta J L, Roberts M
Arch Intern Med. 1986 May;146(5):916-8. doi: 10.1001/archinte.146.5.916.
Eighty-four patients with allergic bronchopulmonary aspergillosis (ABPA) were evaluated for a total of 294 patient-years with a mean observation period of 3.7 years and classified by the stage of ABPA. The largest percentage of patients were in the stage IV (corticosteroid-dependent asthma stage) group. The next largest percentage were in the stage V (fibrotic, end-stage lung disease) group. Of the latter 24 patients, eight had died. In addition, we describe 13 patients with all serologic characteristics of ABPA but without central bronchiectasis. We propose that these patients have seropositive ABPA and represent the earliest cases of it that can be diagnosed in contrast with ABPA with central bronchiectasis in which lung damage is already present.
对84例变应性支气管肺曲霉病（ABPA）患者进行了总计294患者年的评估，平均观察期为3.7年，并根据ABPA分期进行分类。患者比例最大的是IV期（依赖皮质类固醇哮喘期）组。其次比例最大的是V期（纤维化终末期肺病）组。后一组中的24例患者中有8例死亡。此外，我们描述了13例具有ABPA所有血清学特征但无中心性支气管扩张的患者。我们认为这些患者患有血清反应阳性的ABPA，是与已有肺损伤的中心性支气管扩张型ABPA相比可诊断的最早病例。
