Otorhinolaryngology Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND) University of Palermo, 90100 Palermo, Italy.
Hygiene and Preventive Medicine Section, Department of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialities (PROMISE), University of Palermo, 90100 Palermo, Italy.
Int J Environ Res Public Health. 2022 Feb 2;19(3):1713. doi: 10.3390/ijerph19031713.
Tumours of the nasal septum are a rare and heterogeneous group of lesions in the sinonasal tract. The management of the different lesions of this site is debated. The aim of this study is to share our experience on a rare clinical condition and stimulate other centres to publish theirs.
We retrospectively analysed the databases of sinonasal tumours treated at the Sections of Otolaryngology (ENT) of two University Hospitals (Palermo and Genova) between 2012 and 2020.
From the two databases, a cohort of 32 patients with tumours of nasal septum were selected. All patients underwent an endoscopic examination. Large tumours underwent preoperative computed tomography (CT) scan without contrast medium. In 22 (68.7%) cases, the preoperative radiologic evaluation also included magnetic resonance imaging (MRI) with gadolinium to obtain a better differentiation of the lesions and study the vascular pattern. All the large lesions were biopsied under endoscopic guidance using local anaesthesia; the same approach was used to remove the tumours and their attachment with safe resection margins.
While malignant lesions require an excision of the mass with resection of all layers of the nasal septum, benign lesions must be typed according to histological considerations in order to plan the most appropriate type of surgical resection.
鼻中隔肿瘤是鼻窦鼻腔内一种罕见且具有异质性的病变。对于该部位的不同病变的处理方式存在争议。本研究旨在分享我们对一种罕见临床情况的经验,并鼓励其他中心发表相关经验。
我们回顾性分析了 2012 年至 2020 年期间,两个大学医院(巴勒莫和热那亚)耳鼻喉科(ENT)科室治疗的鼻窦肿瘤数据库。
从两个数据库中,我们选择了 32 名鼻中隔肿瘤患者的队列。所有患者均接受了内镜检查。大肿瘤行术前无造影剂的计算机断层扫描(CT)。22 例(68.7%)患者的术前影像学评估还包括磁共振成像(MRI)加钆,以更好地区分病变并研究血管模式。所有大肿瘤均在局部麻醉下经内镜引导下活检;采用相同方法切除肿瘤及其与安全切除边缘的附着组织。
恶性病变需要切除肿块并切除鼻中隔的所有层,而良性病变必须根据组织学考虑进行分型,以便规划最合适的手术切除类型。