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感染梅毒的HIV阳性患者的扁桃体卡波西肉瘤

Tonsillar Kaposi's Sarcoma in HIV Positive Patient with Syphilis Infection.

作者信息

Lorusso Francesco, Di Vincenzo Salvatore Alberto, Campofiorito Valerio, Sireci Federico, Immordino Angelo, Dispenza Francesco

机构信息

Otorhinolaryngology Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, AOUP "Paolo Giaccone", Via del Vespro, 133, 90127 Palermo, Italy.

出版信息

Iran J Otorhinolaryngol. 2024 Mar;36(2):437-441. doi: 10.22038/IJORL.2024.72743.3463.

Abstract

INTRODUCTION

Since the introduction of Highly Active Anti-Retroviral Therapy (HAART), there has been a significant increase in the survival of HIV-infected patients. Consequently, there has been increased attention on the potential neoplastic pathologies, such as Kaposi's sarcoma, associated with AIDS in these individuals.

CASE REPORT

In this case report we present, for the first time, a patient affected by Kaposi's sarcoma of the palatine tonsil with a concomitant syphilis infection. The patient underwent enlarged tonsillectomy and continued antiretroviral therapy. There were no signs of disease recurrence at a 12-month follow-up.

CONCLUSIONS

Despite the rarity of tonsillar localization of Kaposi's sarcoma, it should be suspected in the presence of an HIV-infected patient. Tonsillectomy effectively controls local disease, but comprehensive patient management requires a multidisciplinary team of healthcare professionals, including infectious disease specialists, pathologists, and oncologists who work together to provide high-quality and coordinated care.

摘要

引言

自从高效抗逆转录病毒疗法(HAART)问世以来,HIV感染患者的生存率显著提高。因此,人们越来越关注这些个体中与艾滋病相关的潜在肿瘤性病变,如卡波西肉瘤。

病例报告

在本病例报告中,我们首次呈现了一名患有腭扁桃体卡波西肉瘤并伴有梅毒感染的患者。该患者接受了扁桃体扩大切除术,并继续接受抗逆转录病毒治疗。在12个月的随访中未发现疾病复发迹象。

结论

尽管卡波西肉瘤在扁桃体部位罕见,但在HIV感染患者中应予以怀疑。扁桃体切除术可有效控制局部疾病,但全面的患者管理需要多学科医疗专业团队,包括传染病专家、病理学家和肿瘤学家共同努力,以提供高质量和协调一致的护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62b0/10925962/db70e8611a2f/ijo-36-437-g001.jpg

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