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关于研究方法和实验模型的批判性分析,以研究根管材料导致的牙齿变色。

A critical analysis of research methods and experimental models to study tooth discolouration from endodontic materials.

机构信息

Private Practice, Brisbane, Queensland, Australia.

UWA Dental School, The University of Western Australia, Perth, Western Australia, Australia.

出版信息

Int Endod J. 2022 Apr;55 Suppl 2:370-383. doi: 10.1111/iej.13708. Epub 2022 Mar 1.

DOI:10.1111/iej.13708
PMID:35165907
Abstract

As a range of materials used in endodontics may cause tooth discolouration, exploration of factors responsible for the darkening of the tooth crown or root is warranted. This narrative review paper discusses the range of technical factors that apply in laboratory studies that assess endodontic discolouration. As an example of how these factors operate, particular examples relating to discolouration caused by endodontic medicaments containing tetracycline antibiotics are used. Following the PRILE 2021 guideline approach, a summary of key variables to be addressed in the methodology for laboratory studies is presented, to inform future work.

摘要

由于一系列用于牙髓学的材料可能导致牙齿变色,因此有必要探索导致牙冠或牙根变暗的因素。本文综述了实验室研究中评估牙髓变色的一系列技术因素。作为这些因素如何作用的一个例子,特别例外地使用了与含有四环素类抗生素的根管药物引起的变色有关的例子。根据 PRILE 2021 指南方法,提出了实验室研究方法中需要解决的关键变量的摘要,以指导未来的工作。

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Int Endod J. 2022 Apr;55 Suppl 2:370-383. doi: 10.1111/iej.13708. Epub 2022 Mar 1.
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