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评估儿童癌症治疗后的迟发性心脏毒性效应。

Assessment of late cardiotoxic effects in patients treated for cancer in childhood.

机构信息

Department of Internal Medicine/Cardiology, St. Anne's University Hospital, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.

出版信息

Cancer Med. 2022 Apr;11(8):1763-1768. doi: 10.1002/cam4.4564. Epub 2022 Feb 15.

DOI:10.1002/cam4.4564
PMID:35166044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9041077/
Abstract

Graphical AbstractThe aim was to assess the late cardiotoxic effects in young adults treated for various cancer types in childhood using echocardiography and 24-h ECG Holter monitoring.

摘要

图表摘要

本研究旨在通过超声心动图和 24 小时心电图 Holter 监测评估儿童期接受不同癌症类型治疗的年轻成年人的晚期心脏毒性效应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0eb/9041077/8d104dd2bbe4/CAM4-11-1763-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0eb/9041077/8d104dd2bbe4/CAM4-11-1763-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0eb/9041077/8d104dd2bbe4/CAM4-11-1763-g002.jpg

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本文引用的文献

1
Cardiac Surveillance for Early Detection of Late Subclinical Cardiac Dysfunction in Childhood Cancer Survivors After Anthracycline Therapy.蒽环类药物治疗后儿童癌症幸存者晚期亚临床心脏功能障碍早期检测的心脏监测
Front Oncol. 2021 May 14;11:624057. doi: 10.3389/fonc.2021.624057. eCollection 2021.
2
Effect of anthracycline therapy on myocardial function and markers of fibrotic remodelling in childhood cancer survivors.蒽环类药物治疗对儿童癌症幸存者心肌功能和纤维化重塑标志物的影响。
Eur Heart J Cardiovasc Imaging. 2021 Mar 22;22(4):435-442. doi: 10.1093/ehjci/jeaa093.
3
Doxorubicin and its proarrhythmic effects: A comprehensive review of the evidence from experimental and clinical studies.
多柔比星及其致心律失常作用：实验和临床研究证据的综合综述。
Pharmacol Res. 2020 Jan;151:104542. doi: 10.1016/j.phrs.2019.104542. Epub 2019 Nov 13.
4
Right ventricular function in long-term adult survivors of childhood lymphoma and acute lymphoblastic leukaemia.儿童淋巴瘤和急性淋巴细胞白血病成年长期幸存者的右心室功能
Eur Heart J Cardiovasc Imaging. 2016 Jul;17(7):735-41. doi: 10.1093/ehjci/jew018. Epub 2016 Feb 24.
5
Impaired exercise capacity and left ventricular function in long-term adult survivors of childhood acute lymphoblastic leukemia.儿童急性淋巴细胞白血病成年长期存活者的运动能力和左心室功能受损。
Pediatr Blood Cancer. 2015 Aug;62(8):1437-43. doi: 10.1002/pbc.25492. Epub 2015 Apr 1.
6
Long-term cardiovascular toxicity in children, adolescents, and young adults who receive cancer therapy: pathophysiology, course, monitoring, management, prevention, and research directions: a scientific statement from the American Heart Association.接受癌症治疗的儿童、青少年和年轻成年人的长期心血管毒性：病理生理学、病程、监测、管理、预防及研究方向：美国心脏协会的科学声明
Circulation. 2013 Oct 22;128(17):1927-95. doi: 10.1161/CIR.0b013e3182a88099. Epub 2013 Sep 30.
7
Modifiable risk factors and major cardiac events among adult survivors of childhood cancer.儿童癌症成年幸存者的可改变风险因素和主要心脏事件。
J Clin Oncol. 2013 Oct 10;31(29):3673-80. doi: 10.1200/JCO.2013.49.3205. Epub 2013 Sep 3.
8
Reduced cardiorespiratory fitness in adult survivors of childhood acute lymphoblastic leukemia.儿童期急性淋巴细胞白血病成年幸存者的心肺功能降低。
Pediatr Blood Cancer. 2013 Aug;60(8):1358-64. doi: 10.1002/pbc.24492. Epub 2013 Feb 15.
9
Exercise capacity in long-term survivors of pediatric cancer: an analysis from the Cardiac Risk Factors in Childhood Cancer Survivors Study.儿童癌症幸存者的运动能力：来自儿童癌症幸存者心脏风险因素研究的分析。
Pediatr Blood Cancer. 2013 Apr;60(4):663-8. doi: 10.1002/pbc.24410. Epub 2012 Dec 19.
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Systolic and diastolic dysfunction in long-term adult survivors of childhood cancer.儿童癌症长期幸存者的收缩和舒张功能障碍。
Eur J Cancer. 2011 Nov;47(16):2453-62. doi: 10.1016/j.ejca.2011.05.023. Epub 2011 Jun 21.