Schmidt H, Fischedick A R, Peters P E, von Lengerke H J
Dtsch Med Wochenschr. 1986 May 23;111(21):816-20. doi: 10.1055/s-2008-1068537.
In three patients with acute leukemia candidal abscesses occurred. In spite of ready response to induction chemotherapy, septic fever as well as hepatic and splenic enlargement were observed. Broad-spectrum antibiotics did not improve the patients' condition either. Ultrasonography of liver and spleen revealed multiple, small echolucent foci and target lesions. Computed tomography detected multiple, hypodense foci 1-2 cm in diameter; after contrast medium application there was no enhancement. Candidal septicaemia was demonstrated in all three patients.
3例急性白血病患者发生了念珠菌性脓肿。尽管诱导化疗反应良好,但仍观察到败血症发热以及肝脾肿大。广谱抗生素也未能改善患者的病情。肝脏和脾脏超声检查显示多个小的无回声灶和靶病变。计算机断层扫描检测到多个直径1-2厘米的低密度灶;应用造影剂后无强化。所有3例患者均证实有念珠菌败血症。