Gustavo Duarte Pimentel, Universidade Federal de Goiás, Goiânia, Goiás, MA: 74605-080, Brasil. E-mail:
J Nutr Health Aging. 2022;26(2):187-189. doi: 10.1007/s12603-022-1738-3.
The aim of this study was to investigate the association between fatigue and phase angle (PA) in patients with chronic kidney disease (CKD) on hemodialysis (HD).
A cross-sectional study with older patients than 18 years diagnosed with CKD undergoing HD. From 160 (58.36±15.05 years) patients, (n=96; 60%) are men. Body mass and height were assessed using a portable scale and stadiometer, followed by body mass index (BMI) calculus. The bioimpedance electrical analysis was performed using the Bodystat QuadScan 4000. The sample size was dichotomized in two groups, using the median of our sample, either normal when PA ≥5.4º, or low when the PA <5.4º. The Chalder fatigue questionnaire was used the assess the fatigue. The multiple regression was applied to assess the association between fatigue questionnaire and PA.
Were considered normal PA≥5.4º (n=78, 48.8%) and low PA<5.4º (n=82, 51.2%). The patients of the PA<5.4º group are older compared to the PA≥5.4º group (63.1±15.1 vs. 53.3±13.4 years, p<0.001). There was no association between PA and fatigue score in the crude model (OR: 1.02, 95%CI: 0.96-1.08, p=0.47) and after confounding variables (OR: 1.03, CI: 0.95-1.12, p=0.43).
In HD patients, we found that patients with lower PA values are older. In addition, we did not find association between fatigue and PA.
本研究旨在探讨慢性肾脏病（CKD）血液透析（HD）患者疲劳与相位角（PA）的关系。
这是一项横断面研究，纳入年龄大于 18 岁、诊断为 CKD 并接受 HD 治疗的患者。在 160 名患者中（58.36±15.05 岁），有 96 名（60%）为男性。采用便携式秤和测高仪评估体重和身高，随后计算体重指数（BMI）。使用 Bodystat QuadScan 4000 进行生物阻抗电分析。根据我们样本的中位数将样本大小分为两组，当 PA≥5.4°时为正常，当 PA<5.4°时为低。采用 Chalder 疲劳问卷评估疲劳。应用多元回归分析评估疲劳问卷与 PA 之间的关系。
将 PA≥5.4°（n=78，48.8%）定义为正常，PA<5.4°（n=82，51.2%）定义为低。PA<5.4°组的患者年龄大于 PA≥5.4°组（63.1±15.1 岁比 53.3±13.4 岁，p<0.001）。在未调整模型中（OR：1.02，95%CI：0.96-1.08，p=0.47）和调整混杂因素后（OR：1.03，CI：0.95-1.12，p=0.43），PA 与疲劳评分之间均无关联。
在 HD 患者中，我们发现 PA 值较低的患者年龄较大。此外，我们未发现疲劳与 PA 之间存在关联。
