Key Laboratory of Regional Ecological Environment Analysis and Pollution Control of West Guangxi, College Chemistry & Environment Engineering, Baise University, Baise, 533000, China.
State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, College of Chemistry and Pharmacy, Guangxi Normal University, Guilin, 541004, China.
Mikrochim Acta. 2022 Feb 15;189(3):107. doi: 10.1007/s00604-022-05188-7.
A near-infrared nitrogen and sulfur co-doped carbon dot (N,S-CD)-based ratiometric fluorescent probe is proposed that is synthesized via hydrothermal approach using glutathione and formamide as precursor for sensing and imaging of Zn. The prepared N,S-CDs facilitate binding with Zn owing to N and S atom doping. The ratio (I/I) of fluorescence intensity at 650 nm and 680 nm increased with the concentrations of Zn when the excitation wavelength was 415 nm. The linearity range was 0.01 to 1.0 μM Znwith a detection limit of 5.0 nM Zn. The proposed probe was applied to label-free monitoring of Zn in real samples and fluorescent imaging of Zn in living cells, which confirmed its promising applications.
一种基于近红外氮硫共掺杂碳点（N，S-CD）的比率荧光探针，通过水热法以谷胱甘肽和甲酰胺为前体制备，用于检测和成像 Zn。由于 N 和 S 原子掺杂，制备的 N，S-CDs 有利于与 Zn 结合。当激发波长为 415nm 时，荧光强度在 650nm 和 680nm 处的比值（I/I）随着 Zn 浓度的增加而增加。Zn 的线性范围为 0.01 至 1.0μM，Zn 的检测限为 5.0nM。该探针用于对实际样品中 Zn 的无标记监测和活细胞中 Zn 的荧光成像，证实了其具有广阔的应用前景。
Zotero 插件