Tsukube Takuro
Division of Cardiovascular Surgery, Japanese Red Cross Kobe Hospital & Hyogo Emergency Medical Center, Kobe, Japan.
Asian Cardiovasc Thorac Ann. 2023 Jan;31(1):20-25. doi: 10.1177/02184923211060574. Epub 2022 Feb 15.
While the outcome of aortic repair for acute type-A aortic dissection has improved, overall mortality among patients who developed acute type-A aortic dissection remains extremely high. Hypotension in acute type-A aortic dissection patients is a critical condition that is associated with increased in-hospital mortality and neurologic events. The underlying causes of shock include acute aortic regurgitation, cardiac tamponade, and myocardial infarction. The most reasonable initial approach is to administer intravenous fluids to improve blood pressure, increase preload and cardiac output, and ensure adequate end-organ perfusion. Cardiac tamponade-induced hypotension associated with aortic rupture has been identified as a major risk factor for perioperative mortality in patients with acute type-A aortic dissection. In addition, the most serious complications of acute type-A aortic dissection include preoperative cardiopulmonary arrest, especially out-of-hospital cardiopulmonary arrest. Recent advances in rapid transportation and diagnosis, and the introduction of extracorporeal cardiopulmonary resuscitation, have resulted in an increase in the number of patients with cardiopulmonary arrest related to acute type-A aortic dissection. However, controversy continues to surround treatment strategies, surgical indications, and the timing of surgery on such patients. This review, therefore, discusses decision-making and the managerial issues surrounding acute type-A dissection presenting with shock, cardiac tamponade, and cardiac arrest.
虽然急性A型主动脉夹层的主动脉修复结果有所改善,但发生急性A型主动脉夹层的患者总体死亡率仍然极高。急性A型主动脉夹层患者的低血压是一种危急情况,与住院死亡率和神经系统事件增加相关。休克的潜在原因包括急性主动脉瓣反流、心脏压塞和心肌梗死。最合理的初始方法是静脉输注液体以改善血压、增加前负荷和心输出量,并确保足够的终末器官灌注。与主动脉破裂相关的心脏压塞引起的低血压已被确定为急性A型主动脉夹层患者围手术期死亡的主要危险因素。此外,急性A型主动脉夹层最严重的并发症包括术前心肺骤停,尤其是院外心肺骤停。快速运输和诊断方面的最新进展以及体外心肺复苏的引入,导致与急性A型主动脉夹层相关的心肺骤停患者数量增加。然而,关于此类患者的治疗策略、手术指征和手术时机仍存在争议。因此,本综述讨论了围绕伴有休克、心脏压塞和心脏骤停的急性A型夹层的决策和管理问题。