Suppr超能文献

垂直距骨切除术治疗后下肢主要截肢的相关风险因素。

Risks Factors Associated With Major Lower Extremity Amputation After Vertical Contour Calcanectomy.

机构信息

Resident Physician, Department of Plastic Surgery, MedStar Georgetown University Hospital, Washington DC.

Limb Preservation and Deformity Correction Fellow, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD.

出版信息

J Foot Ankle Surg. 2022 Sep-Oct;61(5):1046-1051. doi: 10.1053/j.jfas.2022.01.013. Epub 2022 Jan 19.

Abstract

The primary aim of the study is to determine risks for major lower extremity amputation after undergoing Vertical Contour Calcanectomy. Subanalysis was performed comparing patients who underwent Vertical Contour Calcanectomy who were fully ambulatory to those who were partially or nonambulatory postoperatively. Within the cohort of 63 patients included in the Vertical Contour Calcanectomy 85.71% (54/63) of patients had diabetes mellitus, 53.97% (34/63) had peripheral arterial disease, and 19.05% (12/63) had Charcot Neuroarthropathy. Multivariate logistic regression, found that (1) patients that underwent primary closure at the time of the Vertical Contour Calcanectomy, were 79.9% more likely (odds ratio [OR] 0.20; 95% confidence interval [CI] 0.04-0.96) to have limb salvage and that (2) female patients were 85.4% less likely compared to male patients (OR 0.15; 95% CI 0.02-0.99) to undergo major lower extremity amputation. Patients with coronary artery disease were 5.2 times more likely (OR 5.18; 95% CI 1.120-23.94) and patients that were nonambulatory preoperatively, were 10.3 times more likely (OR 10.28; 95% CI 1.60-66.26), to be partially or nonambulatory after Vertical Contour Calcanectomy. Primary closure at time of Vertical Contour Calcanectomy significantly decreases the risk of major lower extremity amputation, and diminished preoperative ambulatory status as well as coronary artery disease makes it less likely that patients return to full ambulation after Vertical Contour Calcanectomy.

摘要

本研究的主要目的是确定接受 Vertical Contour Calcanectomy 后进行大下肢截肢的风险。亚分析比较了完全术后步行的患者与部分或非术后步行的患者。在纳入的 63 例 Vertical Contour Calcanectomy 患者中,85.71%(54/63)的患者患有糖尿病,53.97%(34/63)的患者患有外周动脉疾病,19.05%(12/63)的患者患有夏科氏神经关节病。多变量逻辑回归发现,(1)在进行 Vertical Contour Calcanectomy 时进行一期缝合的患者,保肢的可能性增加 79.9%(优势比[OR]0.20;95%置信区间[CI]0.04-0.96),并且(2)女性患者与男性患者相比,大下肢截肢的可能性降低 85.4%(OR 0.15;95%CI 0.02-0.99)。患有冠状动脉疾病的患者发生大下肢截肢的可能性增加 5.2 倍(OR 5.18;95%CI 1.120-23.94),术前非步行患者发生大下肢截肢的可能性增加 10.3 倍(OR 10.28;95%CI 1.60-66.26)。Vertical Contour Calcanectomy 时的一期缝合显著降低了大下肢截肢的风险,术前步行状态的降低以及冠状动脉疾病使患者在 Vertical Contour Calcanectomy 后更不可能完全恢复步行。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验