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骨髓中出现伴有癌相关血栓性微血管病的印戒细胞癌转移,为首发表现。

Signet ring cell carcinoma metastasis in the bone marrow accompanied by cancer related thrombotic microangiopathy as a first presentation.

机构信息

Department of Hematology, Bursa City Hospital, Bursa, Turkey.

Department of Pathology, Bursa City Hospital, Bursa, Turkey.

出版信息

Niger J Clin Pract. 2022 Feb;25(2):211-214. doi: 10.4103/njcp.njcp_622_20.

DOI:10.4103/njcp.njcp_622_20
PMID:35170451
Abstract

Cancer related thrombotic microangiopathies usually cause a diagnostic dilemma for hematologists and clinicians. In this case report, we presented a fifty-nine-year-old man who was admitted to our hospital with microangiopathic hemolytic anemia and thrombocytopenia due to the carcinoma metastasis to the bone marrow. As a result of rapid evaluations, it was revealed that the histological subtype of the cancer was signet ring cell carcinoma, and despite all the interventions, the patient died at a very short time after the initial presentation. Regardless of all the innovations in the diagnosis and treatment of thrombotic microangiopathies, cancer-associated thrombotic microangiopathy is still fatal and deadly today.

摘要

癌症相关的血栓性微血管病通常会给血液科医生和临床医生带来诊断上的难题。在本病例报告中,我们介绍了一位 59 岁的男性患者,因骨髓转移癌导致微血管性溶血性贫血和血小板减少而入院。经过快速评估,发现癌症的组织学亚型为印戒细胞癌,尽管进行了所有干预措施,患者在初次就诊后很短的时间内就死亡了。尽管在血栓性微血管病的诊断和治疗方面有了所有的创新,但癌症相关的血栓性微血管病今天仍然是致命的。

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引用本文的文献

1
Cancer-related thrombotic microangiopathy and disseminated intravascular coagulation in a patient with bone marrow carcinomatosis of unknown primary origin: A case report.患者骨髓转移癌来源不明伴癌相关血栓性微血管病和弥散性血管内凝血 1 例报告
Cancer Rep (Hoboken). 2024 Mar;7(3):e2036. doi: 10.1002/cnr2.2036.