Grisoni E R, Gauderer M W, Wolfson R N, Izant R J
J Pediatr Surg. 1986 Apr;21(4):358-61. doi: 10.1016/s0022-3468(86)80204-4.
During a 52-month span, 14,324 ultrasonographic examinations were performed on 9,453 pregnant patients. One-hundred and fifty-one anatomical malformations were found in 122 fetuses (1.29%). Our analysis of patients referred to the perinatal center for ultrasonography indicates that the number of high risk patients has increased, and a parallel increase of neonatal surgical anomalies has resulted. An analysis of fetuses concluded that anomalies of the: gastrointestinal tract had improved care, deaths occurred due to associated anomalies or severe prematurity; genitourinary system received earlier diagnosis and treatment; central nervous system/musculoskeletal system/hydrops--no difference in management, treatment or outcome was noted; teratoma/cystic hygroma--did not effect treatment; cardiovascular system--inutero medical treatment by digitalization of the mother was possible. Paradoxically, an increase in the mortality of diaphragmatic hernia patients was noted and concluded to be secondary to the extremely early detection of this anomaly.
在52个月的时间里,对9453名孕妇进行了14324次超声检查。在122例胎儿(1.29%)中发现了151例解剖结构畸形。我们对转诊至围产期中心进行超声检查的患者分析表明,高危患者数量有所增加,同时新生儿手术异常情况也相应增加。对胎儿的分析得出结论:胃肠道畸形的护理有所改善,死亡是由相关畸形或严重早产导致的;泌尿生殖系统得到了更早的诊断和治疗;中枢神经系统/肌肉骨骼系统/水肿——在管理、治疗或结果方面未发现差异;畸胎瘤/囊状水瘤——不影响治疗;心血管系统——可通过母亲洋地黄化进行宫内药物治疗。矛盾的是,发现膈疝患者的死亡率有所上升,结论是这是该异常情况极早期发现的继发结果。