Raeburn D, Rodger I W, Hay D W, Fedan J S
Life Sci. 1986 Apr 21;38(16):1499-505. doi: 10.1016/0024-3205(86)90563-1.
Isolated guinea-pig and rabbit airway smooth muscle preparations lacking cartilage are less able to contract, in response to methacholine, histamine and K+, in the absence of extracellular Ca2+ than cartilage-containing preparations removed from the same animal. Cartilage apparently provides utilizable Ca2+ for contraction of airway smooth muscle. The presence of cartilage, therefore, affects the apparent dependence of the isolated smooth muscle on extracellular Ca2+ for contraction.
与从同一动物身上取下的含软骨的气道平滑肌制剂相比，去除软骨的离体豚鼠和兔气道平滑肌制剂在无细胞外钙离子的情况下，对乙酰甲胆碱、组胺和钾离子的收缩反应能力较弱。软骨显然为气道平滑肌的收缩提供了可利用的钙离子。因此，软骨的存在影响了离体平滑肌收缩对细胞外钙离子的明显依赖性。
