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[中子和γ射线全身照射后大鼠淋巴细胞表面膜的早期变化]

[Early changes in the lymphocyte surface membrane of rats after whole-body irradiation with neutrons and gamma rays].

作者信息

Mikhaĭlov V F, Vodolazskaia N A, Rakova I A

出版信息

Radiobiologiia. 1986 Mar-Apr;26(2):253-7.

PMID:3517944
Abstract

Biochemical changes in lymphocyte plasma membranes were studied 3 and 18 h after whole-body exposure of rats to neutrons and gamma-rays at doses from 2 to 6 Gy. It was shown that fast neutrons, with an average energy of 1.5-2.0 MeV, increased the rate of lipid peroxidation more markedly than gamma-rays did. In addition, there was an increase in the number of free aminogroups on the thymocyte surface. Dose- and time-dependent parameters of changes in the aminogroup content on the cellular surface were quantitatively different after the effect of radiation with different LET.

摘要

在大鼠全身暴露于剂量为2至6 Gy的中子和γ射线后3小时和18小时,研究了淋巴细胞质膜中的生化变化。结果表明,平均能量为1.5 - 2.0 MeV的快中子比γ射线更显著地提高了脂质过氧化速率。此外,胸腺细胞表面的游离氨基数量增加。在不同传能线密度(LET)的辐射作用后,细胞表面氨基含量变化的剂量和时间依赖性参数在数量上有所不同。

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