Data Management and Statistics Institute, Dongguk University Ilsan Hospital, Goyang, Korea.
Research Center for Chronic Disease and Environmental Medicine, Dongguk University College of Medicine, Goyang, Korea.
PLoS One. 2022 Feb 18;17(2):e0264213. doi: 10.1371/journal.pone.0264213. eCollection 2022.
Few large-scale studies have been conducted to show the joint effects of mortality associated with physical activity and sedentarism. Therefore, we examined the relationship between all-cause mortality and behavioral patterns among adults in the United States. Data of 17,730 non-institutionalized US civilians aged ≥20 years were extracted from the 2007-2014 National Health and Nutrition Examination Survey. We set the criteria for metabolic equivalents as 600 according to the WHO guideline, and sedentary time as 300 min/day according to the median. The Cox proportional hazards model was adjusted for demographic and lifestyle characteristics. During the 58.54±28.18 months follow-up, all-cause mortality rate was 4% and heart-related and cancer mortality rate was 1%. Participants in the high metabolic equivalents and low sedentary time group had a lower risk of all-cause (hazard ratio = 0.41, 95% confidence interval = 0.34-0.50), cardiovascular (hazard ratio = 0.36; 95% confidence interval = 0.23-0.55), and cancer (hazard ratio = 0.55; 95% confidence interval = 0.37-0.83) mortality, compared to those in the low metabolic equivalents and high sedentary time group. Sufficient physical activity and less sedentary behavior reduce all-cause and cause-specific mortality in adults in the United States, especially cardiovascular mortality among the elderly. Additional nationwide policies to improve behavioral patterns among adults need to be implemented in the United States.
很少有大规模的研究来展示与体力活动和久坐行为相关的死亡率的联合影响。因此,我们在美国成年人中检查了全因死亡率与行为模式之间的关系。从 2007-2014 年全国健康和营养调查中提取了 17730 名非机构化的美国成年人的数据。我们根据世界卫生组织的指南将代谢当量标准定为 600,并根据中位数将久坐时间定为 300 分钟/天。Cox 比例风险模型根据人口统计学和生活方式特征进行了调整。在 58.54±28.18 个月的随访期间,全因死亡率为 4%,与心脏相关的死亡率和癌症死亡率为 1%。在高代谢当量和低久坐时间组中,全因(风险比=0.41,95%置信区间=0.34-0.50)、心血管(风险比=0.36;95%置信区间=0.23-0.55)和癌症(风险比=0.55;95%置信区间=0.37-0.83)死亡率均低于低代谢当量和高久坐时间组。充足的体力活动和较少的久坐行为可降低美国成年人的全因死亡率和特定原因死亡率,尤其是老年人的心血管死亡率。美国需要实施额外的全国性政策来改善成年人的行为模式。